Literature DB >> 22531279

Beyond azide-alkyne click reaction: easy access to 18F-labelled compounds via nitrile oxide cycloadditions.

Boris D Zlatopolskiy1, René Kandler, Diana Kobus, Felix M Mottaghy, Bernd Neumaier.   

Abstract

Radiofluorinated 4-fluorobenzonitrile oxide and N-hydroxy-4-fluorobenzimidoyl chloride rapidly react with different alkenes and alkynes under mild conditions. These cycloadditions are suitable for the preparation of low-molecular weight radiopharmaceuticals and, in a strain-promoted variant, can enable easy labelling of sensitive biopolymers.

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Year:  2012        PMID： 22531279     DOI： 10.1039/c2cc31335a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  6 in total

Review 1.  18 F-Labeling of Sensitive Biomolecules for Positron Emission Tomography.

Authors:  Hema S Krishnan; Longle Ma; Neil Vasdev; Steven H Liang
Journal:  Chemistry       Date:  2017-09-01       Impact factor: 5.236

Review 2.  Click Chemistry and Radiochemistry: The First 10 Years.

Authors:  Jan-Philip Meyer; Pierre Adumeau; Jason S Lewis; Brian M Zeglis
Journal:  Bioconjug Chem       Date:  2016-11-22       Impact factor: 4.774

3.  Novel valdecoxib derivatives by ruthenium(ii)-promoted 1,3-dipolar cycloaddition of nitrile oxides with alkynes - synthesis and COX-2 inhibition activity.

Authors:  Silvia Roscales; Nicole Bechmann; Daniel Holger Weiss; Martin Köckerling; Jens Pietzsch; Torsten Kniess
Journal:  Medchemcomm       Date:  2018-02-13       Impact factor: 3.597

4.  Nitrone-Modified Gold Nanoparticles: Synthesis, Characterization, and Their Potential as 18F-Labeled Positron Emission Tomography Probes via I-SPANC.

Authors:  Sara Ghiassian; Lihai Yu; Pierangelo Gobbo; Ali Nazemi; Tommaso Romagnoli; Wilson Luo; Leonard G Luyt; Mark S Workentin
Journal:  ACS Omega       Date:  2019-11-08

Review 5.  18F-labeling using click cycloadditions.

Authors:  Kathrin Kettenbach; Hanno Schieferstein; Tobias L Ross
Journal:  Biomed Res Int       Date:  2014-05-27       Impact factor: 3.411

Review 6.  Recent Advances in Bioorthogonal Click Chemistry for Efficient Synthesis of Radiotracers and Radiopharmaceuticals.

Authors:  Sajid Mushtaq; Seong-Jae Yun; Jongho Jeon
Journal:  Molecules       Date:  2019-10-02       Impact factor: 4.411
  6 in total

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