Literature DB >> 22530812

Profile of infants born to drug-using mothers: a state-wide audit.

Mohamed E Abdel-Latif1, Julee Oei, Fiona Craig, Kei Lui.   

Abstract

AIMS: To ascertain the characteristics and short-term outcomes of infants born to illicit drug-using mothers in public hospitals in the state of New South Wales and the Australian Capital Territory during 2004.
METHODS: Patients were identified retrospectively by hospital records searches using ICD-10 morbidity codes and records of local Drug and Alcohol Services. Records were reviewed on site. All public hospitals (n= 101) with obstetric services were included.
RESULTS: A total of 879 (1.4%, 95% confidence interval: 1.3-1.5%) drug-using mothers were identified from 62,682 confinements. Opiates (46.8%), amphetamines (23.0%) and polydrug (16.4%) exposure were most common. There were eight stillbirths. Among these 871 infants, prematurity (23.6%) and low birthweight (27.1%) were common and 51.1% were admitted to nurseries for further care. Two infants died. Major congenital anomalies were detected in 15 infants. Pharmacological treatment for withdrawal was required for 202 (23.2%), and 143 (70.8%) infants were discharged home on medication. Infants who completed inpatient pharmacological treatment were hospitalised longer (median 26.0 vs. 12.0 days) and were more likely to be premature (37.3 vs. 14.0%). Child-at-risk notifications affected 40.6% of the infants, and 7.6% were fostered prior to discharge. A total of 333 (38.2%) infants were breastfed at discharge.
CONCLUSIONS: Our regional study highlights a substantial prevalence of drug use in pregnancy with considerable adverse perinatal and hospital outcomes in infants born to these mothers. Coordinated health care and resources are needed to support these mother-infant pairs because of their social, medical and mental-health issues.
© 2012 The Authors. Journal of Paediatrics and Child Health © 2012 Paediatrics and Child Health Division (Royal Australasian College of Physicians).

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Year:  2012        PMID: 22530812     DOI: 10.1111/j.1440-1754.2012.02471.x

Source DB:  PubMed          Journal:  J Paediatr Child Health        ISSN: 1034-4810            Impact factor:   1.954


  5 in total

1.  Characteristics of drug use among pregnant women in the United States: Opioid and non-opioid illegal drug use.

Authors:  Verena E Metz; Qiana L Brown; Silvia S Martins; Joseph J Palamar
Journal:  Drug Alcohol Depend       Date:  2017-12-27       Impact factor: 4.492

2.  Increased Severity of Neonatal Abstinence Syndrome Associated With Concomitant Antenatal Opioid and Benzodiazepine Exposure.

Authors:  Lauren A Sanlorenzo; William O Cooper; Judith A Dudley; Shannon Stratton; Faouzi I Maalouf; Stephen W Patrick
Journal:  Hosp Pediatr       Date:  2019-07-01

3.  Co-occurrence of preconception maternal childhood adversity and opioid use during pregnancy: Implications for offspring brain development.

Authors:  Madeleine C Allen; Nora K Moog; Claudia Buss; Elizabeth Yen; Hanna C Gustafsson; Elinor L Sullivan; Alice M Graham
Journal:  Neurotoxicol Teratol       Date:  2021-09-30       Impact factor: 4.071

Review 4.  Neonatal Opioid Withdrawal Syndrome (NOWS): A Transgenerational Echo of the Opioid Crisis.

Authors:  Andrew E Weller; Richard C Crist; Benjamin C Reiner; Glenn A Doyle; Wade H Berrettini
Journal:  Cold Spring Harb Perspect Med       Date:  2021-03-01       Impact factor: 6.915

5.  Prevalence of Vitamin D Deficiency in a Large Newborn Cohort from Northern United States and Effect of Intrauterine Drug Exposure.

Authors:  Neelakanta Kanike; Krupa Gowri Hospattankar; Amit Sharma; Sarah Worley; Sharon Groh-Wargo
Journal:  Nutrients       Date:  2020-07-14       Impact factor: 5.717

  5 in total

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