Literature DB >> 22528794

Patients with brain tumor-related epilepsy.

Marta Maschio1, Loredana Dinapoli.   

Abstract

Patients with brain tumor-related epilepsy (BTRE) present a complex therapeutic profile and require a unique and multidisciplinary approach. They, in fact, must face two different pathologies at the same time, brain tumor and epilepsy. Therefore, it is necessary to develop a customized treatment plan for each individual with BTRE. This requires a vision of patient management concerned not only with medical therapies related to the oncological disease and to the correct choice of antiepileptic therapies but also with emotional and psychological support for the individual and his/her family. The choice of antiepileptic drugs is challenging for these patients because BTRE is often drug-resistant, has a strong impact on the quality of life, and weighs heavily on public health expenditures. In brain tumor patients, the presence of epilepsy is considered the most important risk factor for long-term disability. The problem of the proper administration of medications and their potential side effects is of great importance, because good seizure control also has a significant impact on the patient's psychological and relational sphere.

Entities:  

Mesh:

Year:  2012        PMID: 22528794     DOI: 10.1007/s11060-012-0867-7

Source DB:  PubMed          Journal:  J Neurooncol        ISSN: 0167-594X            Impact factor:   4.130


  62 in total

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7.  Efficacy and tolerability of zonisamide as add-on in brain tumor-related epilepsy: preliminary report.

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8.  Temozolomide treatment does not affect topiramate and oxcarbazepine plasma concentrations in chronically treated patients with brain tumor-related epilepsy.

Authors:  Marta Maschio; Fiorenzo Albani; Bruno Jandolo; Alessia Zarabla; Manuela Contin; Loredana Dinapoli; Alessandra Fabi; Andrea Pace; Agostino Baruzzi
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  14 in total

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10.  Molecular Classification of Gliomas is Associated with Seizure Control: A Retrospective Analysis.

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