BACKGROUND: Body mass index (BMI) has been suggested to provide clinicopathological information in tumor development and progression in patients with gastric carcinoma. METHODS: The correlation of BMI with clinicopathological features and operation-related factors was analyzed in 308 patients with gastric carcinoma who had undergone distal or total gastrectomy. RESULTS: There was no significant correlation of obesity, indicated by a high value of BMI, with tumor-related factors including survival, or with operation-related factors. On the other hand, more advanced tumors and worse preoperative nutritional and immunological conditions were found in patients with a lower value of BMI. CONCLUSIONS: BMI might be a representation of the physical condition brought about by the extent of tumor progression rather than a factor influencing the factors related to gastric carcinoma.
BACKGROUND: Body mass index (BMI) has been suggested to provide clinicopathological information in tumor development and progression in patients with gastric carcinoma. METHODS: The correlation of BMI with clinicopathological features and operation-related factors was analyzed in 308 patients with gastric carcinoma who had undergone distal or total gastrectomy. RESULTS: There was no significant correlation of obesity, indicated by a high value of BMI, with tumor-related factors including survival, or with operation-related factors. On the other hand, more advanced tumors and worse preoperative nutritional and immunological conditions were found in patients with a lower value of BMI. CONCLUSIONS: BMI might be a representation of the physical condition brought about by the extent of tumor progression rather than a factor influencing the factors related to gastric carcinoma.
Authors: Stephan Gretschel; Frank Christoph; Andreas Bembenek; Lope Estevez-Schwarz; Ulrike Schneider; Peter M Schlag Journal: Ann Surg Oncol Date: 2003-05 Impact factor: 5.344
Authors: Jonathan D Barry; Guy R J C Blackshaw; Paul Edwards; Wyn G Lewis; Paula Murphy; Ilias Hodzovic; Ian W Thompson; Miles C Allison Journal: Gastric Cancer Date: 2003 Impact factor: 7.370
Authors: Frank A Sinicrope; Nathan R Foster; Daniel J Sargent; Michael J O'Connell; Cathryn Rankin Journal: Clin Cancer Res Date: 2010-03-09 Impact factor: 12.531
Authors: Erin F Gillespie; Melony E Sorbero; David A Hanauer; Michael S Sabel; Emily J Herrmann; Laura J Weiser; Christina H Jagielski; Jennifer J Griggs Journal: Ann Surg Oncol Date: 2009-11-07 Impact factor: 5.344