Literature DB >> 22526247

Influence of acute dietary nitrate supplementation on 50 mile time trial performance in well-trained cyclists.

Daryl P Wilkerson1, Giles M Hayward, Stephen J Bailey, Anni Vanhatalo, Jamie R Blackwell, Andrew M Jones.   

Abstract

Dietary nitrate supplementation has been reported to improve short distance time trial (TT) performance by 1-3 % in club-level cyclists. It is not known if these ergogenic effects persist in longer endurance events or if dietary nitrate supplementation can enhance performance to the same extent in better trained individuals. Eight well-trained male cyclists performed two laboratory-based 50 mile TTs: (1) 2.5 h after consuming 0.5 L of nitrate-rich beetroot juice (BR) and (2) 2.5 h after consuming 0.5 L of nitrate-depleted BR as a placebo (PL). BR significantly elevated plasma [NO(2) (-)] (BR: 472 ± 96 vs. PL: 379 ± 94 nM; P < 0.05) and reduced completion time for the 50 mile TT by 0.8 % (BR: 136.7 ± 5.6 vs. PL: 137.9 ± 6.4 min), which was not statistically significant (P > 0.05). There was a significant correlation between the increased post-beverage plasma [NO(2) (-)] with BR and the reduction in TT completion time (r = -0.83, P = 0.01). Power output (PO) was not different between the conditions at any point (P > 0.05) but oxygen uptake ([Formula: see text]O(2)) tended to be lower in BR (P = 0.06), resulting in a significantly greater PO/[Formula: see text]O(2) ratio (BR: 67.4 ± 5.5 vs. PL: 65.3 ± 4.8 W L min(-1); P < 0.05). In conclusion, acute dietary supplementation with beetroot juice did not significantly improve 50 mile TT performance in well-trained cyclists. It is possible that the better training status of the cyclists in this study might reduce the physiological and performance response to NO(3) (-) supplementation compared with the moderately trained cyclists tested in earlier studies.

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Year:  2012        PMID: 22526247     DOI: 10.1007/s00421-012-2397-6

Source DB:  PubMed          Journal:  Eur J Appl Physiol        ISSN: 1439-6319            Impact factor:   3.078


  27 in total

1.  Optimization of nitric oxide chemiluminescence operating conditions for measurement of plasma nitrite and nitrate.

Authors:  Ryon M Bateman; Christopher G Ellis; David J Freeman
Journal:  Clin Chem       Date:  2002-03       Impact factor: 8.327

2.  Dietary nitrate supplementation reduces the O2 cost of walking and running: a placebo-controlled study.

Authors:  Katherine E Lansley; Paul G Winyard; Jonathan Fulford; Anni Vanhatalo; Stephen J Bailey; Jamie R Blackwell; Fred J DiMenna; Mark Gilchrist; Nigel Benjamin; Andrew M Jones
Journal:  J Appl Physiol (1985)       Date:  2010-11-11

3.  Mitochondrial cytochrome oxidase produces nitric oxide under hypoxic conditions: implications for oxygen sensing and hypoxic signaling in eukaryotes.

Authors:  Pablo R Castello; Pamela S David; Travis McClure; Zachary Crook; Robert O Poyton
Journal:  Cell Metab       Date:  2006-04       Impact factor: 27.287

4.  Effects of dietary nitrate on oxygen cost during exercise.

Authors:  F J Larsen; E Weitzberg; J O Lundberg; B Ekblom
Journal:  Acta Physiol (Oxf)       Date:  2007-07-17       Impact factor: 6.311

5.  Nitrate supplementation's improvement of 10-km time-trial performance in trained cyclists.

Authors:  Naomi M Cermak; Martin J Gibala; Luc J C van Loon
Journal:  Int J Sport Nutr Exerc Metab       Date:  2012-02       Impact factor: 4.599

6.  Dietary nitrate supplementation reduces the O2 cost of low-intensity exercise and enhances tolerance to high-intensity exercise in humans.

Authors:  Stephen J Bailey; Paul Winyard; Anni Vanhatalo; Jamie R Blackwell; Fred J Dimenna; Daryl P Wilkerson; Joanna Tarr; Nigel Benjamin; Andrew M Jones
Journal:  J Appl Physiol (1985)       Date:  2009-08-06

7.  Dietary nitrate supplementation enhances muscle contractile efficiency during knee-extensor exercise in humans.

Authors:  Stephen J Bailey; Jonathan Fulford; Anni Vanhatalo; Paul G Winyard; Jamie R Blackwell; Fred J DiMenna; Daryl P Wilkerson; Nigel Benjamin; Andrew M Jones
Journal:  J Appl Physiol (1985)       Date:  2010-05-13

8.  Acute administration of inorganic nitrate reduces VO(2peak) in endurance athletes.

Authors:  Raúl Bescós; Ferran A Rodríguez; Xavier Iglesias; Miguel D Ferrer; Elena Iborra; Antoni Pons
Journal:  Med Sci Sports Exerc       Date:  2011-10       Impact factor: 5.411

9.  Dietary nitrate reduces maximal oxygen consumption while maintaining work performance in maximal exercise.

Authors:  Filip J Larsen; Eddie Weitzberg; Jon O Lundberg; Björn Ekblom
Journal:  Free Radic Biol Med       Date:  2009-11-12       Impact factor: 7.376

10.  Acute blood pressure lowering, vasoprotective, and antiplatelet properties of dietary nitrate via bioconversion to nitrite.

Authors:  Andrew J Webb; Nakul Patel; Stavros Loukogeorgakis; Mike Okorie; Zainab Aboud; Shivani Misra; Rahim Rashid; Philip Miall; John Deanfield; Nigel Benjamin; Raymond MacAllister; Adrian J Hobbs; Amrita Ahluwalia
Journal:  Hypertension       Date:  2008-02-04       Impact factor: 10.190

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  61 in total

Review 1.  "Nutraceuticals" in relation to human skeletal muscle and exercise.

Authors:  Colleen S Deane; Daniel J Wilkinson; Bethan E Phillips; Kenneth Smith; Timothy Etheridge; Philip J Atherton
Journal:  Am J Physiol Endocrinol Metab       Date:  2017-01-31       Impact factor: 4.310

Review 2.  ISSN exercise & sports nutrition review update: research & recommendations.

Authors:  Chad M Kerksick; Colin D Wilborn; Michael D Roberts; Abbie Smith-Ryan; Susan M Kleiner; Ralf Jäger; Rick Collins; Mathew Cooke; Jaci N Davis; Elfego Galvan; Mike Greenwood; Lonnie M Lowery; Robert Wildman; Jose Antonio; Richard B Kreider
Journal:  J Int Soc Sports Nutr       Date:  2018-08-01       Impact factor: 5.150

3.  Effect of nitrate supplementation on hepatic blood flow and glucose homeostasis: a double-blind, placebo-controlled, randomized control trial.

Authors:  Anthony I Shepherd; Daryl P Wilkerson; Jon Fulford; Paul G Winyard; Nigel Benjamin; Angela C Shore; Mark Gilchrist
Journal:  Am J Physiol Gastrointest Liver Physiol       Date:  2016-07-14       Impact factor: 4.052

4.  Acute Beet Juice Supplementation Does Not Improve 30- or 60-second Maximal Intensity Performance in Anaerobically Trained Athletes.

Authors:  Scott A Conger; Clare M Zamzow; Matthew E Darnell
Journal:  Int J Exerc Sci       Date:  2021-04-01

Review 5.  Dietary nitrate supplementation and exercise performance.

Authors:  Andrew M Jones
Journal:  Sports Med       Date:  2014-05       Impact factor: 11.136

6.  Effects of sodium phosphate and beetroot juice supplementation on repeated-sprint ability in females.

Authors:  Christopher L Buck; Timothy Henry; Kym Guelfi; Brian Dawson; Lars R McNaughton; Karen Wallman
Journal:  Eur J Appl Physiol       Date:  2015-06-16       Impact factor: 3.078

7.  The relationship between plasma and salivary NOx.

Authors:  William H Clodfelter; Swati Basu; Crystal Bolden; Patricia C Dos Santos; S Bruce King; Daniel B Kim-Shapiro
Journal:  Nitric Oxide       Date:  2015-04-21       Impact factor: 4.427

8.  No effect of acute L-arginine supplementation on O₂ cost or exercise tolerance.

Authors:  Anni Vanhatalo; Stephen J Bailey; Fred J DiMenna; Jamie R Blackwell; Gareth A Wallis; Andrew M Jones
Journal:  Eur J Appl Physiol       Date:  2013-02-20       Impact factor: 3.078

9.  Impact of dietary nitrate supplementation via beetroot juice on exercising muscle vascular control in rats.

Authors:  Scott K Ferguson; Daniel M Hirai; Steven W Copp; Clark T Holdsworth; Jason D Allen; Andrew M Jones; Timothy I Musch; David C Poole
Journal:  J Physiol       Date:  2012-10-15       Impact factor: 5.182

10.  Dietary nitrate supplementation improves team sport-specific intense intermittent exercise performance.

Authors:  Lee J Wylie; Magni Mohr; Peter Krustrup; Sarah R Jackman; Georgios Ermιdis; James Kelly; Matthew I Black; Stephen J Bailey; Anni Vanhatalo; Andrew M Jones
Journal:  Eur J Appl Physiol       Date:  2013-02-01       Impact factor: 3.078

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