Literature DB >> 225261

Interferon production by mammalian cells grown in a serum-free medium.

R W Pumper, L Molander.   

Abstract

Interferon, produced by rabbit heart cells grown in a serum-free medium, failed to protect rabbit heart serum-free cells, but protected rabbit heart serum-containing-medium cells against vaccinia and vesicular stomatitis virus. Interferon produced in serum-free cells had a greater species specificity than that produced in serum-containing media. The difference in activity was shown to be due to lack of adsorption by serum-free-medium cells.

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Year:  1979        PMID: 225261     DOI: 10.1007/bf02616147

Source DB:  PubMed          Journal:  In Vitro        ISSN: 0073-5655


  14 in total

1.  PURIFIED INTERFERONS: PHYSICAL PROPERTIES AND SPECIES SPECIFICITY.

Authors:  T C MERIGAN
Journal:  Science       Date:  1964-08-21       Impact factor: 47.728

2.  An interferon-like inhibitor of viral multiplication from malignant cells (the viral autoinhibition phenomenon).

Authors:  C CHANY
Journal:  Virology       Date:  1961-04       Impact factor: 3.616

3.  Multiplication of vaccinia virus in serum-free and serum-containing cell cultures.

Authors:  R W PUMPER; L J ALFRED; D L SACKETT
Journal:  Nature       Date:  1960-01-09       Impact factor: 49.962

4.  AN INHIBITOR OF VIRAL ACTIVITY APPEARING IN INFECTED CELL CULTURES.

Authors:  M Ho; J F Enders
Journal:  Proc Natl Acad Sci U S A       Date:  1959-03       Impact factor: 11.205

5.  Characterization of a fetal calf serum-derived molecule reactive with human natural antibodies: its occurrence in tissue culture-grown type C RNA viruses.

Authors:  H W Snyder; M Fox
Journal:  J Immunol       Date:  1978-02       Impact factor: 5.422

6.  Relative sensitivities of viruses to different species of interferon.

Authors:  W E Stewart; W D Scott; S E Sulkin
Journal:  J Virol       Date:  1969-08       Impact factor: 5.103

7.  A human interferon that crosses the species line.

Authors:  J Desmyter; W E Rawls; J L Melnick
Journal:  Proc Natl Acad Sci U S A       Date:  1968-01       Impact factor: 11.205

8.  A serum substitute for mammalian cells in culture. I. Biological efficacy of whole and fractionated peptone dialysate.

Authors:  W G Taylor; M J Taylor; N J Lewis; R W Pumper
Journal:  Proc Soc Exp Biol Med       Date:  1972-01

9.  Defectiveness of interferon production and of rubella virus interference in a line of African green monkey kidney cells (Vero).

Authors:  J Desmyter; J L Melnick; W E Rawls
Journal:  J Virol       Date:  1968-10       Impact factor: 5.103

10.  VARIATIONS IN THE ABILITIES OF SEVERAL LINES OF L CELLS TO PRODUCE AND TO BE AFFECTED BY INTERFERON.

Authors:  R Z LOCKART
Journal:  J Bacteriol       Date:  1965-01       Impact factor: 3.490

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