Yang Gao1, Bin Lu, Zhihui Hou, Fangfang Yu, Huili Cao, Lei Han, Runze Wu. 1. Department of Radiology, Cardiovascular Institute and Fu Wai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, #167 Bei-Li-Shi Street, Beijing 100037, China.
Abstract
OBJECTIVES: To investigate the radiation dose and image quality of prospective ECG-triggering dual-source CT angiography in infants with complex congenital heart disease (CHD) in comparison with retrospective ECG-gated scanning. METHODS:Ninety-six infants less than 1 year old (60/36 male/female, age: 4.8 ± 2.7 months, weight: 5.8 ± 1.8 kg) with complex CHD were enrolled. Three image acquisition protocols were set: group 1: 80 kV, 100 mA, retrospective ECG-gated protocol; group 2: 80 kV, 100 mA, prospective ECG-triggering protocol with acquisition window of 380 ms; group 3: 80 kV, 100 mA, prospective ECG-triggering protocol with acquisition window of 200 ms. Patients were selected to any one of the protocols randomly. The signal-to-noise ratios (SNR) were calculated in the ascending aorta and the pulmonary artery trunk. Image quality was assessed by a five-point score. A score of <3 represents non-diagnostic. Effective radiation dose (ED) was calculated. RESULTS:Image quality score of groups 1, 2 and 3 were 4.1 ± 0.4, 4.0 ± 0.6 and 4.2 ± 0.6 (p = 0.224). SNR of ascending aorta and pulmonary artery trunk among them had no statistical difference (all p>0.05). The average ED (median) of groups 1, 2 and 3 were 1.17 ± 0.07 mSv (1.25 mSv), 0.72 ± 0.24 mSv (0.78 mSv) and 0.48 ± 0.41 mSv (0.39 mSv). Any two of the three groups had significant differences (all p<0.001). CONCLUSION: Prospective ECG-triggering DSCT angiography associated with a significantly lower ED than retrospective protocol, while maintaining image quality for diagnosis. Prospective ECG-triggering DSCT angiography could be used as a very important second-line diagnostic tool in infants with complex CHD.
RCT Entities:
OBJECTIVES: To investigate the radiation dose and image quality of prospective ECG-triggering dual-source CT angiography in infants with complex congenital heart disease (CHD) in comparison with retrospective ECG-gated scanning. METHODS: Ninety-six infants less than 1 year old (60/36 male/female, age: 4.8 ± 2.7 months, weight: 5.8 ± 1.8 kg) with complex CHD were enrolled. Three image acquisition protocols were set: group 1: 80 kV, 100 mA, retrospective ECG-gated protocol; group 2: 80 kV, 100 mA, prospective ECG-triggering protocol with acquisition window of 380 ms; group 3: 80 kV, 100 mA, prospective ECG-triggering protocol with acquisition window of 200 ms. Patients were selected to any one of the protocols randomly. The signal-to-noise ratios (SNR) were calculated in the ascending aorta and the pulmonary artery trunk. Image quality was assessed by a five-point score. A score of <3 represents non-diagnostic. Effective radiation dose (ED) was calculated. RESULTS: Image quality score of groups 1, 2 and 3 were 4.1 ± 0.4, 4.0 ± 0.6 and 4.2 ± 0.6 (p = 0.224). SNR of ascending aorta and pulmonary artery trunk among them had no statistical difference (all p>0.05). The average ED (median) of groups 1, 2 and 3 were 1.17 ± 0.07 mSv (1.25 mSv), 0.72 ± 0.24 mSv (0.78 mSv) and 0.48 ± 0.41 mSv (0.39 mSv). Any two of the three groups had significant differences (all p<0.001). CONCLUSION: Prospective ECG-triggering DSCT angiography associated with a significantly lower ED than retrospective protocol, while maintaining image quality for diagnosis. Prospective ECG-triggering DSCT angiography could be used as a very important second-line diagnostic tool in infants with complex CHD.
Authors: Li-Ping Yao; Li Zhang; Ju Mei; Fang-Bao Ding; Hui-Ming Li; Ming Ding; Xin Yang; Xiao-Ming Li; Kun Sun Journal: Exp Ther Med Date: 2017-11-27 Impact factor: 2.447