Literature DB >> 22524916

Computed tomography findings of bowel wall thickening: its significance and relationship to endoscopic abnormalities.

M M Uzzaman1, A Alam, M S Nair, R Borgstein, L Meleagros.   

Abstract

INTRODUCTION: The aim of this study was to conduct retrospective analysis of abdominopelvic computed tomography (CT) reports, identifying those patients in whom bowel wall thickening (BWT) was observed, and to correlate these reports with subsequent endoscopic evaluation.
METHODS: Formal reports for all patients undergoing abdominopelvic CT between February 2007 and September 2009 were reviewed. Where patients were identified as having colorectal 'wall thickening', results of subsequent endoscopic evaluations were documented. Only those patients with a report of BWT who had follow-up endoscopy (colonoscopy, sigmoidoscopy) were included in the analysis.
RESULTS: A total of 165 patients were included. Abnormalities on endoscopy at the exact site of the BWT on CT were found in 95 patients (57.58%); in 36 cases (21.82%) this was a malignant lesion. BWT of the transverse colon was significantly more likely to correspond to an endoscopic finding of cancer than other sites (p=0.034). Rectal bleeding was reported significantly more often in patients with BWT and neoplastic disease on endoscopy compared with those with normal endoscopy (p=0.04). Excluding patients with inflammatory/diverticular lesions, 59.02% of Caucasians had a neoplastic lesion at the site of reported BWT, significantly higher than the other ethnic groups (p=0.008). There were 38 patients (23.03%) who did not present with bowel symptoms and, of these, 6 were diagnosed subsequently with colorectal cancer.
CONCLUSIONS: This study supports endoscopic evaluation to investigate patients with CT evidence of BWT, especially in cases involving the transverse colon, in Caucasian patients or in association with symptoms of rectal bleeding.

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Year:  2012        PMID: 22524916      PMCID: PMC3954182          DOI: 10.1308/003588412x13171221498983

Source DB:  PubMed          Journal:  Ann R Coll Surg Engl        ISSN: 0035-8843            Impact factor:   1.891


  19 in total

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Authors:  M Macari; E J Balthazar
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Review 2.  Unusual causes of colonic wall thickening on computed tomography.

Authors:  D R Turner; G Markose; M J Arends; C S Ng; A H Freeman
Journal:  Clin Radiol       Date:  2003-03       Impact factor: 2.350

3.  Incidental findings of thickening luminal gastrointestinal organs on computed tomography: an absolute indication for endoscopy.

Authors:  Qiang Cai; Deborah A Baumgarten; John P Affronti; J Patrick Waring
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Authors:  Won Chang Shin; Myeong Ja Jeong
Journal:  Korean J Gastroenterol       Date:  2005-06

5.  Colonoscopy for colonic wall thickening at computed tomography: a worthwhile pursuit?

Authors:  Brian D Nicholson; Rachel Hyland; Bjorn J Rembacken; Mark Denyer; Mark A Hull; Damian J M Tolan
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Authors:  D C Rockey; R A Halvorsen; J L Higgins; J P Cello
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Review 8.  CT evaluation of wall thickening in the alimentary tract.

Authors:  R K Desai; J R Tagliabue; S A Wegryn; D M Einstein
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10.  The clinical significance of incidental computer tomography finding of gastrointestinal luminal wall thickening as evaluated by endoscopy.

Authors:  Wissam Bleibel; Jorge E Guerrero; Stephen Kim; Luiz Leao; Taranga Ghosh; Thomas J Kenney
Journal:  Dig Dis Sci       Date:  2007-03-24       Impact factor: 3.199

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1.  The performance of routine computed tomography for the detection of colorectal cancer.

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8.  Significance of ileal and/or cecal wall thickening on abdominal computed tomography in a tropical country.

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