| Literature DB >> 22523584 |
Nawi Ng1, Mohammad Hakimi, Ailiana Santosa, Peter Byass, Siswanto Agus Wilopo, Stig Wall.
Abstract
BACKGROUND: Empirical studies on the association between self-rated health (SRH) and subsequent mortality are generally lacking in low- and middle-income countries. The evidence on whether socio-economic status and education modify this association is inconsistent. This study aims to fill these gaps using longitudinal data from a Health and Demographic Surveillance System (HDSS) site in Indonesia.Entities:
Mesh:
Year: 2012 PMID: 22523584 PMCID: PMC3327655 DOI: 10.1371/journal.pone.0035308
Source DB: PubMed Journal: PLoS One ISSN: 1932-6203 Impact factor: 3.240
Baseline characteristics of the study subjects in Purworejo HDSS, Indonesia.
| Characteristics | Men (n = 5420) | Women (n = 6333) |
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| 50–59 | 2040 (37.6) | 2304 (36.4) |
| 60–69 | 1781 (32.9) | 2264 (35.8) |
| 70–79 | 1231 (22.7) | 1413 (22.3) |
| 80+ | 368 (6.8) | 352 (5.6) |
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| No formal education | 869 (16.0) | 2571 (40.6) |
| Any formal education | 4551 (84.0) | 3762 (59.4) |
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| 1st quintile (lowest SES) | 1044 (19.3) | 1350 (21.3) |
| 2nd quintile | 1031 (19.0) | 1286 (20.3) |
| 3rd quintile | 1114 (20.6) | 1276 (20.2) |
| 4th quintile | 1151 (21.2) | 1236 (19.5) |
| 5th quintile (highest SES) | 1080 (19.9) | 1185 (18.7) |
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| Married | 4718 (87.0) | 3682 (58.1) |
| Not married | 702 (13.0) | 2651 (41.9) |
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| Lives with others in household | 5201 (96.0) | 5644 (89.1) |
| Lives alone | 219 (4.0) | 689 (10.9) |
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| No disease | 4484 (82.7) | 5072 (80.1) |
| Any disease | 936 (17.3) | 1261 (19.9) |
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| No disability | 5323 (98.2) | 6223 (98.3) |
| Any disability | 97 (1.8) | 110 (1.7) |
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| Rural village | 4942 (91.2) | 5718 (90.3) |
| Small urban settlement | 478 (8.8) | 615 (9.7) |
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| 599 (11.1) | 600 (9.5) |
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| 193194 | 227756 |
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| 3.1 | 2.6 |
Note:
indicates significant difference in the characteristics between men and women (p<0.05).
Age-adjusted mortality rates for self-rated health across educational levels in Purworejo HDSS, Indonesia; stratified by sex.
| Men | Women | |||
| No education | Any education | No education | Any education | |
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| N | 869 | 4551 | 2571 | 3762 |
| Subsequent deaths, n (%) | 140 (9.0) | 459 (8.9) | 345 (8.3) | 255 (7.2) |
| Age-adjusted death rate | 4.3 | 2.6 | 3.9 | 2.1 |
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| N (%) | 535 (67.7) | 3316 (72.6) | 1520 (63.8) | 2674 (68.6) |
| Subsequent deaths, n (%) | 63 (5.9) | 237 (6.1) | 157 (6.0) | 131 (5.0) |
| Age-adjusted death rate | 3.0 | 1.8 | 3.0 | 1.5 |
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| N (%) | 292 (28.9) | 1136 (25.2) | 931 (32.5) | 985 (28.1) |
| Subsequent deaths, n (%) | 58 (14.2) | 187 (15.3) | 139 (11.1) | 95 (11.0) |
| Age-adjusted death rate | 5.7 | 4.3 | 4.3 | 2.9 |
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| N (%) | 41 (2.9) | 95 (1.9) | 119 (3.2) | 100 (2.9) |
| Subsequent deaths, n (%) | 19 (39.1) | 35 (36.6) | 49 (38.4) | 29 (33.3) |
| Age-adjusted death rate | 14.8 | 11.8 | 14.3 | 10.5 |
Note: All percentages in bracket are age-adjusted percentages. Death rate is calculated per 1,000 person-months of observation.
Age-adjusted mortality rates for self-rated health by socioeconomic status in Purworejo HDSS, Indonesia; stratified by sex.
| Men | Women | |||
| Poorest SES quintile | 2nd–5th SES quintiles | Poorest SES quintile | 2nd–5th SES quintiles | |
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| N | 1044 | 4376 | 1360 | 4983 |
| Subsequent deaths, n (%) | 149 (10.1) | 450 (8.5) | 139 (7.6) | 461 (7.8) |
| Age-adjusted death rate | 4.0 | 2.9 | 2.9 | 2.6 |
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| N (%) | 677 (67.6) | 3174 (72.9) | 834 (63.7) | 3360 (67.5) |
| Subsequent deaths, n (%) | 64 (6.2) | 236 (6.0) | 62 (5.4) | 226 (5.5) |
| Age-adjusted death rate | 2.5 | 2.0 | 2.1 | 1.9 |
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| N (%) | 327 (29.2) | 1101 (24.9) | 466 (33.0) | 1450 (29.1) |
| Subsequent deaths, n (%) | 69 (17.9) | 176 (14.2) | 62 (10.9) | 172 (11.1) |
| Age-adjusted death rate | 6.3 | 4.5 | 3.7 | 3.4 |
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| N (%) | 40 (2.8) | 96 (1.9) | 48 (2.8) | 171 (3.0) |
| Subsequent deaths, n (%) | 16 (34.4) | 38 (38.4) | 15 (32.6) | 63 (37.3) |
| Age-adjusted death rate | 11.1 | 12.4 | 10.9 | 12.5 |
Note: All percentages in bracket are age-adjusted percentages. Death rate is calculated per 1,000 person-months of observation.
Association between each independent variable and subsequent mortality, adjusted by age.
| Characteristics | Hazard Ratio (95% CI) for men | Hazard Ratio (95% CI) for women |
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| Moderate | 1.88 (1.59–2.24) | 1.50 (1.26–1.78) |
| Bad | 3.64 (2.71–4.90) | 4.66 (3.62–6.00) |
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| No formal education | 1.03 (0.85–1.26) | 1.22 (1.02–1.45) |
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| Poorest quintile | 1.17 (0.97–1.41) | 0.96 (0.79–1.16) |
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| Not married | 1.33 (1.09–1.62) | 1.40 (1.17–1.67) |
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| Lives alone | 1.05 (0.76–1.46) | 1.05 (0.83–1.32) |
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| Any disease | 2.10 (1.77–2.49) | 1.84 (1.56–2.18) |
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| Any disability | 2.35 (1.66–3.34) | 2.71 (1.94–3.79) |
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| Small urban settlement | 1.73 (1.38–2.17) | 1.10 (0.86–1.41) |
Note: CI = confidence interval.
Model building and assessment of effect modification of education and socio-economic status on the association between self-rated health and mortality among men and women in Purworejo District.
| Characteristics | Hazard Ratio (95% CI) for men | Hazard Ratio (95% CI) for women | ||||
| Model 1 | Model 2 | Model 3 | Model 1 | Model 2 | Model 3 | |
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| Moderate | 1.88 (1.58–2.23) | 1.72 (1.45–2.05) | 1.68 (1.36–2.08) | 1.49 (1.25–1.77) | 1.37 (1.14–1.63) | 1.58 (1.20–2.08) |
| Bad | 3.60 (2.68–4.85) | 2.81 (2.07–3.81) | 2.96 (2.02–4.35) | 4.60 (3.57–5.93) | 3.81 (2.93–4.97) | 4.88 (3.23–7.38) |
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| No formal education | 0.98 (0.80–1.20) | 1.03 (0.84–1.26) | 1.08 (0.81–1.44) | 1.18 (0.99–1.42) | 1.17 (0.97–1.40) | 1.37 (1.07–1.76) |
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| Poorest quintile | 1.11 (0.92–1.35) | 1.26 (1.03–1.53) | 1.18 (0.89–1.58) | 0.92 (0.76–1.12) | 0.98 (0.80–1.20) | 0.97 (0.72–1.29) |
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| Moderate health with no education | - | - | 1.58 (1.14–2.20) | - | - | 1.61 (1.22–2.14) |
| Bad health with no education | - | - | 3.84 (2.14–6.89) | - | - | 4.54 (3.08–6.68) |
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| Moderate health with poorest quintile | - | - | 2.48 (1.83–3.34) | - | - | 1.65 (1.14–2.40) |
| Bad health with poorest quintile | - | - | 2.44 (1.28–4.66) | - | - | 4.32 (2.23–8.36) |
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| 60–69 | 2.82 (2.14–3.71) | 2.77 (2.11–3.65) | 2.76 (2.10–3.64) | 2.46 (1.88–3.22) | 2.26 (1.72–2.96) | 2.22 (1.69–2.92) |
| 70–79 | 4.76 (3.62–6.24) | 4.30 (3.27–5.65) | 4.31 (3.28–5.67) | 4.23 (3.20–5.59) | 3.57 (2.68–4.76) | 3.53 (2.65–4.71) |
| 80+ | 8.21 (6.06–11.1) | 7.10 (5.21–9.66) | 7.07 (5.19–9.63) | 7.31 (5.31–10.1) | 5.67 (4.06–7.93) | 5.62 (4.03–7.85) |
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| Not married | - | 1.37 (1.10–1.71) | 1.37 (1.10–1.71) | - | 1.40 (1.16–1.69) | 1.40 (1.16–1.69) |
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| Lives alone | - | 0.83 (0.57–1.20) | 0.83 (0.58–1.21) | - | 0.93 (0.73–1.19) | 0.93 (0.73–1.19) |
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| Any disease | - | 1.86 (1.56–2.21) | 1.86 (1.56–2.22) | - | 1.64 (1.38–1.95) | 1.64 (1.38–1.96) |
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| Any disability | - | 1.94 (1.36–2.77) | 1.99 (1.39–2.83) | - | 1.80 (1.27–2.54) | 1.85 (1.31–2.62) |
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| Small urban settlement | - | 1.75 (1.39–2.22) | 1.75 (1.39–2.22) | - | 1.02 (0.79–1.32) | 1.02 (0.79–1.32) |
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| −4798.0 (df = 7) | −4754.6 (df = 12) | −4753.0 (df = 16) | −4859.0 (df = 7) | −4832.0 (df = 12) | −4830.1 (df = 16) |
Figure 1Effect modification of education and socio-economic status on the association between self-rated health and mortality, using women with good health, good SES and had any education as reference category.