Literature DB >> 22522647

Shared medical decision-making: considering what options to present based on an ethical analysis of the treatment of brain tumors in very young children.

Deena Levine1, Kenneth Cohen, David Wendler.   

Abstract

The treatment of brain tumors in very young children poses both a therapeutic challenge and a bioethical quandary. The administration of craniospinal radiation after surgery offers the greatest chance for cure but causes severe neurocognitive damage. As a result, current practice does not offer parents the option of full-dose postoperative craniospinal radiation. Some may regard this approach as inappropriate medical paternalism, while others may consider it an example of responsible therapeutics. Evaluation of this dilemma reveals principles which can guide clinicians in determining which treatment options to present to their patients or surrogates, in the context of shared medical decision-making.
Copyright © 2012 Wiley Periodicals, Inc.

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Year:  2012        PMID: 22522647      PMCID: PMC3374065          DOI: 10.1002/pbc.24189

Source DB:  PubMed          Journal:  Pediatr Blood Cancer        ISSN: 1545-5009            Impact factor:   3.167


  29 in total

Review 1.  Symptoms experienced by family members of patients in intensive care units.

Authors:  Jennifer L McAdam; Kathleen Puntillo
Journal:  Am J Crit Care       Date:  2009-05       Impact factor: 2.228

Review 2.  Survival of very young children with medulloblastoma (primitive neuroectodermal tumor of the posterior fossa) treated with craniospinal irradiation.

Authors:  F H Saran; P H Driever; C Thilmann; S Mose; P Wilson; G Sharpe; I A Adamietz; H D Böttcher
Journal:  Int J Radiat Oncol Biol Phys       Date:  1998-12-01       Impact factor: 7.038

3.  Do no harm.

Authors:  A R Jonsen
Journal:  Ann Intern Med       Date:  1978-06       Impact factor: 25.391

4.  Contrasting parents' and pediatricians' perspectives on shared decision-making in ADHD.

Authors:  Alexander G Fiks; Cayce C Hughes; Angela Gafen; James P Guevara; Frances K Barg
Journal:  Pediatrics       Date:  2010-12-20       Impact factor: 7.124

5.  Cancer statistics, 2010.

Authors:  Ahmedin Jemal; Rebecca Siegel; Jiaquan Xu; Elizabeth Ward
Journal:  CA Cancer J Clin       Date:  2010-07-07       Impact factor: 508.702

6.  Treatment of medulloblastoma with postoperative chemotherapy alone: an SFOP prospective trial in young children.

Authors:  Jacques Grill; Christian Sainte-Rose; Anne Jouvet; Jean-Claude Gentet; Odile Lejars; Didier Frappaz; François Doz; Xavier Rialland; Fabienne Pichon; Anne-Isabelle Bertozzi; Pascal Chastagner; Dominique Couanet; Jean-Louis Habrand; Marie-Anne Raquin; Marie-Cécile Le Deley; Chantal Kalifa
Journal:  Lancet Oncol       Date:  2005-08       Impact factor: 41.316

Review 7.  Parental refusals of medical treatment: the harm principle as threshold for state intervention.

Authors:  Douglas S Diekema
Journal:  Theor Med Bioeth       Date:  2004

8.  Predicting change in academic abilities after conformal radiation therapy for localized ependymoma.

Authors:  Heather M Conklin; Chenghong Li; Xiaoping Xiong; Robert J Ogg; Thomas E Merchant
Journal:  J Clin Oncol       Date:  2008-08-20       Impact factor: 44.544

Review 9.  Management of and prognosis with medulloblastoma: therapy at a crossroads.

Authors:  Roger J Packer; Gilbert Vezina
Journal:  Arch Neurol       Date:  2008-11

10.  Impact of radiation avoidance on survival and neurocognitive outcome in infant medulloblastoma.

Authors:  L Lafay-Cousin; E Bouffet; C Hawkins; A Amid; A Huang; D J Mabbott
Journal:  Curr Oncol       Date:  2009-12       Impact factor: 3.677

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  2 in total

Review 1.  Approaches for Discussing Clinical Trials with Pediatric Oncology Patients and Their Families.

Authors:  Lindsay J Blazin; Andrea Cuviello; Holly Spraker-Perlman; Erica C Kaye
Journal:  Curr Oncol Rep       Date:  2022-03-08       Impact factor: 5.075

2.  Parental Considerations Regarding Cure and Late Effects for Children With Cancer.

Authors:  Katie A Greenzang; Hasan Al-Sayegh; Clement Ma; Mehdi Najafzadeh; Eve Wittenberg; Jennifer W Mack
Journal:  Pediatrics       Date:  2020-04-13       Impact factor: 7.124

  2 in total

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