| Literature DB >> 22521133 |
Yi-xin Ou1, Yao-yao Li, Xiao-ming Qian, Yue-mao Shen.
Abstract
Thirteen diterpenoids, named radianspenes A-M (1-13), including three lactams radianspenes J (10), K (11) and L (12) and one dimer radianspene M (13), were isolated from fermentation products of the higher fungal strain Coprinus radians M65. All these compounds possessing guanacastane skeleton were evaluated for antitumor activity using MDA-MB-435 cell line. Radianspene C exhibited inhibitory activity with IC(50) of 0.91 μM.Entities:
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Year: 2012 PMID： 22521133 DOI： 10.1016/j.phytochem.2012.03.002
Source DB: PubMed Journal: Phytochemistry ISSN： 0031-9422 Impact factor: 4.072