| Literature DB >> 22520716 |
Giovanni Manfredi1, Andrea Solfanelli, Giorgia Dimitri, Ilaria Cuomo, Gabriele Sani, Giorgio D Kotzalidis, Paolo Girardi.
Abstract
A Caucasian, male, young adult with recurrent agitated depression and suicidal ideation received lithium and oral olanzapine. His white blood cell count was normal at that time. Due to unsatisfactory response, he received 4 mg/day risperidone. While symptoms improved, leukopenia emerged, specifically directed towards neutrophils. Upon risperidone discontinuation, white blood cell count returned to reference values within 1 week. As symptom control was satisfactory, we attempted no risperidone rechallenge. Accurate blood testing must accompany atypical antipsychotic drug administration since blood dyscrasias are always possible with these drugs.Entities:
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Year: 2012 PMID： 22520716 DOI： 10.1016/j.genhosppsych.2012.03.009
Source DB: PubMed Journal: Gen Hosp Psychiatry ISSN： 0163-8343 Impact factor: 3.238