Literature DB >> 22520637

High-performance liquid chromatography-mass spectrometry and evaporative light-scattering detector to compare phenolic profiles of muscadine grapes.

Qi You1, Feng Chen, Julia L Sharp, Xi Wang, Yuru You, Chuanji Zhang.   

Abstract

Evaporative light scattering detector (ELSD) is considered as a universal detector able to detect almost any compound. This study successfully established a HPLC-ELSD method for the simultaneous determination of phenolic acids, flavonoids and anthocyanins in muscadine grape. Twenty-four phenolics, including 5 anthocyanins, were identified by HPLC-UV-MS, ten of them were selected to calibrate the ELSD. Results from the ELSD quantification suggested that gallic acid, proanthocyanidins, and ellagic acid were the main phenolics in muscadines. In addition, antioxidant tests suggested that the extracts of muscadine grapes possessed strong antioxidant activities. All extracts had a high total phenolic content (TPC). High total anthocyanins contents (TAC) were found in Noble muscadine, and high proanthocyanidins content (TPA) in the seed portion.
Copyright © 2012 Elsevier B.V. All rights reserved.

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Year:  2012        PMID: 22520637     DOI: 10.1016/j.chroma.2012.03.086

Source DB:  PubMed          Journal:  J Chromatogr A        ISSN: 0021-9673            Impact factor:   4.759


  7 in total

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Authors:  Alexandre Giacobbo; Bruna Bernar Dias; Bruna Onorevoli; Andréa Moura Bernardes; Maria Norberta de Pinho; Elina Bastos Caramão; Eliseu Rodrigues; Rosângela Assis Jacques
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3.  Construction of PEGylated boronate-affinity-oriented imprinting magnetic nanoparticles for ultrasensitive detection of ellagic acid from beverages.

Authors:  Meng-Ying Chen; Jin-Ye Lang; Chen-Chen Bai; Shi-Song Yu; Xiang-Jin Kong; Lin-Yi Dong; Xian-Hua Wang
Journal:  Anal Bioanal Chem       Date:  2022-07-12       Impact factor: 4.478

4.  A Polyphenol-Rich Extract From Muscadine Grapes Inhibits Triple-Negative Breast Tumor Growth.

Authors:  Marianne Collard; Patricia E Gallagher; E Ann Tallant
Journal:  Integr Cancer Ther       Date:  2020 Jan-Dec       Impact factor: 3.279

Review 5.  Natural Health Products (NHP's) and Natural Compounds as Therapeutic Agents for the Treatment of Cancer; Mechanisms of Anti-Cancer Activity of Natural Compounds and Overall Trends.

Authors:  Benjamin Scaria; Siddhartha Sood; Christopher Raad; Jana Khanafer; Rahul Jayachandiran; Alaina Pupulin; Sahibjot Grewal; Michael Okoko; Mansi Arora; Lauren Miles; Siyaram Pandey
Journal:  Int J Mol Sci       Date:  2020-11-11       Impact factor: 5.923

6.  Transcriptome Profiling During Muscadine Berry Development Reveals the Dynamic of Polyphenols Metabolism.

Authors:  Ahmed Ismail; Ahmed G Darwish; Minkyu Park; Pranavkumar Gajjar; Violeta Tsolova; Karam F A Soliman; Islam El-Sharkawy
Journal:  Front Plant Sci       Date:  2022-02-02       Impact factor: 5.753

7.  Muscadine grape skin extract inhibits prostate cancer cells by inducing cell-cycle arrest, and decreasing migration through heat shock protein 40.

Authors:  Diane N Ignacio; Kimberly D Mason; Ezra C Hackett-Morton; Christopher Albanese; Lymor Ringer; William D Wagner; Paul C Wang; Michael A Carducci; Sushant K Kachhap; Channing J Paller; Janet Mendonca; Leo Li-Ying Chan; Bo Lin; Diane K Hartle; Jeffrey E Green; Collis A Brown; Tamaro S Hudson
Journal:  Heliyon       Date:  2019-01-16
  7 in total

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