Literature DB >> 22517339

Voriconazole-induced phototoxicity in children.

Sara Bernhard1, Kristin Kernland Lang, Roland A Ammann, Sonja Lüer, Kurt Leibundgut, Miriam Diepold, Christoph Aebi.   

Abstract

Voriconazole is used in antifungal prophylaxis. We performed a retrospective review of immunocompromised children receiving prophylaxis with voriconazole during major hospital renovation, who developed phototoxic skin reactions. The overall incidence of phototoxic skin reactions was 33%. A voriconazole dose of ≥6 mg/kg of body weight per dose twice daily was associated with a significantly greater risk to develop phototoxic skin reactions compared with lower doses.

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Year:  2012        PMID： 22517339     DOI： 10.1097/INF.0b013e3182566311

Source DB:  PubMed          Journal:  Pediatr Infect Dis J        ISSN： 0891-3668            Impact factor:   2.129


  8 in total

1.  Successful management of voriconazole-associated hyponatremia with therapeutic drug monitoring.

Authors:  Ren-ai Xu; Guan-yang Lin; Lu-feng Hu; Da-wei Shi; Xiao-lan Ye; Yun-jie Liu; Xiao-feng Pan; Chun-hong Zhang; Xiu-hua Zhang
Journal:  Antimicrob Agents Chemother       Date:  2013-02-12       Impact factor: 5.191

2.  Recurrent erythematous plaques on sun-exposed sites in an African American boy with chronic granulomatous disease.

Authors:  Mamina M Turegano; Chyi-Chia R Lee; Harry L Malech; Suk S De Ravin; Edward W Cowen; Isaac Brownell
Journal:  J Am Acad Dermatol       Date:  2014-03       Impact factor: 11.527

3.  Voriconazole N-oxide and its ultraviolet B photoproduct sensitize keratinocytes to ultraviolet A.

Authors:  K Ona; D H Oh
Journal:  Br J Dermatol       Date:  2015-07-20       Impact factor: 9.302

4.  Therapeutic drug monitoring in voriconazole-associated hyponatremia.

Authors:  Ren-Ai Xu; Shuang-Li Zheng; Li-Li Xiao; Xue-Ding Cai; Xi-Xi Lai; Guan-Yang Lin; Lu-Feng Hu; Chun-Hong Zhang; Zhi-Sheng Xu; Xiu-Hua Zhang
Journal:  Med Mycol Case Rep       Date:  2013-06-19

5.  Voriconazole exposure regulates distinct cell-cycle and terminal differentiation pathways in primary human keratinocytes.

Authors:  M Mansh; L Ing; M Dimon; A Celli; T M Mauro; S T Arron
Journal:  Br J Dermatol       Date:  2017-01-17       Impact factor: 9.302

6.  Significance of monitoring plasma concentration of voriconazole in a patient with liver failure: A case report.

Authors:  Xiaoyan Liu; Haibin Su; Jingjing Tong; Jing Chen; Haozhen Yang; Long Xiao; Jinhua Hu; Lina Zhang
Journal:  Medicine (Baltimore)       Date:  2017-10       Impact factor: 1.889

Review 7.  Pharmacokinetics and pharmacodynamics of antifungals in children: clinical implications.

Authors:  Julie Autmizguine; Jeffrey T Guptill; Michael Cohen-Wolkowiez; Daniel K Benjamin; Edmund V Capparelli
Journal:  Drugs       Date:  2014-06       Impact factor: 11.431

Review 8.  Pediatric Invasive Aspergillosis.

Authors:  Rachel L Wattier; Lynn Ramirez-Avila
Journal:  J Fungi (Basel)       Date:  2016-06-13
  8 in total

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