Literature DB >> 22516969

The dosimetric impact of leaf interdigitation and leaf width on VMAT treatment planning in Pinnacle: comparing Pareto fronts.

Z van Kesteren1, T M Janssen, E Damen, C van Vliet-Vroegindeweij.   

Abstract

To evaluate in an objective way the effect of leaf interdigitation and leaf width on volumetric modulated arc therapy plans in Pinnacle. Three multileaf collimators (MLCs) were modeled: two 10 mm leaf width MLCs, with and without interdigitating leafs, and a 5 mm leaf width MLC with interdigitating leafs. Three rectum patients and three prostate patients were used for the planning study. In order to compare treatment techniques in an objective way, a Pareto front comparison was carried out. 200 plans were generated in an automated way, per patient per MLC model, resulting in a total of 3600 plans. From these plans, Pareto-optimal plans were selected which were evaluated for various dosimetric variables. The capability of leaf interdigitation showed little dosimetric impact on the treatment plans, when comparing the 10 mm leaf width MLC with and without leaf interdigitation. When comparing the 10 mm leaf width MLC with the 5 mm leaf width MLC, both with interdigitating leafs, improvement in plan quality was observed. For both patient groups, the integral dose was reduced by 0.6 J for the thin MLC. For the prostate patients, the mean dose to the anal sphincter was reduced by 1.8 Gy and the conformity of the V(95%) was reduced by 0.02 using the thin MLC. The V(65%) of the rectum was reduced by 0.1% and the dose homogeneity with 1.5%. For rectum patients, the mean dose to the bowel was reduced by 1.4 Gy and the mean dose to the bladder with 0.8 Gy for the thin MLC. The conformity of the V(95%) was equivalent for the 10 and 5 mm leaf width MLCs for the rectum patients. We have objectively compared three types of MLCs in a planning study for prostate and rectum patients by analyzing Pareto-optimal plans which were generated in an automated way. Interdigitation of MLC leafs does not generate better plans using the SmartArc algorithm in Pinnacle. Changing the MLC leaf width from 10 to 5 mm generates better treatment plans although the clinical relevance remains to be proven.

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Year:  2012        PMID: 22516969     DOI: 10.1088/0031-9155/57/10/2943

Source DB:  PubMed          Journal:  Phys Med Biol        ISSN: 0031-9155            Impact factor:   3.609


  8 in total

1.  Single arc volumetric-modulated arc therapy is sufficient for nasopharyngeal carcinoma: a dosimetric comparison with dual arc VMAT and dynamic MLC and step-and-shoot intensity-modulated radiotherapy.

Authors:  Zhong-Hua Ning; Jin-Ming Mu; Jian-Xue Jin; Xiao-Dong Li; Qi-Lin Li; Wen-Dong Gu; Jin Huang; Yang Han; Hong-Lei Pei
Journal:  Radiat Oncol       Date:  2013-10-14       Impact factor: 3.481

2.  Impact of MLC leaf width on volumetric-modulated arc therapy planning for head and neck cancers.

Authors:  Caroline Lafond; Enrique Chajon; Anne Devillers; Guillaume Louvel; Sandra Toublanc; Mickael Olivier; Antoine Simon; Renaud De Crevoisier; Jean-Pierre Manens
Journal:  J Appl Clin Med Phys       Date:  2013-11-08       Impact factor: 2.102

3.  Dosimetric impact of multileaf collimator leaf width according to sophisticated grade of technique in the IMRT and VMAT planning for pituitary adenoma lesion.

Authors:  Soo-Min Chae; Ki Woong Lee; Seok Hyun Son
Journal:  Oncotarget       Date:  2016-11-22

4.  Is High Definition MLC Dosimetrically Superior to Standard Definition MLC for SIB-SBRT for Carcinoma Prostate.

Authors:  Bijina T K; K M Ganesh; Pichandi A
Journal:  Asian Pac J Cancer Prev       Date:  2019-12-01

5.  Dosimetric sensitivity of leaf width on volumetric modulated arc therapy plan quality: an objective approach.

Authors:  Ghulam Murtaza; Muhammad Shamshad; Munir Ahmed; Shahid Mehmood; Ehsan Ullah Khan
Journal:  Rep Pract Oncol Radiother       Date:  2022-03-22

6.  Impact of MLC properties and IMRT technique in meningioma and head-and-neck treatments.

Authors:  Steffi Kantz; Matthias Söhn; Almut Troeller; Michael Reiner; Helmut Weingandt; Markus Alber; Claus Belka; Ute Ganswindt
Journal:  Radiat Oncol       Date:  2015-09-02       Impact factor: 3.481

7.  A treatment planning study comparing Elekta VMAT and fixed field IMRT using the varian treatment planning system eclipse.

Authors:  Samuel Peters; Hans Schiefer; Ludwig Plasswilm
Journal:  Radiat Oncol       Date:  2014-07-10       Impact factor: 3.481

8.  Capability of leaf interdigitation with different inverse planning strategies in Monaco: an investigation of representative tumour sites.

Authors:  Jinghao Duan; Xiangjuan Meng; Tonghai Liu; Yong Yin
Journal:  Radiat Oncol       Date:  2016-06-17       Impact factor: 3.481

  8 in total

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