Literature DB >> 22516717

A semi-automated system for the routine production of copper-64.

Maiko Kume1, Paul C Carey, Gregory Gaehle, Evelyn Madrid, Thomas Voller, William Margenau, Michael J Welch, Suzanne E Lapi.   

Abstract

An automated system for the production of high specific activity (64)Cu via the irradiation of electroplated enriched (64)Ni targets has been developed. We have been operating this system continually on a biweekly or weekly basis for more than two years. Since the inception of this automated production system, (October 1, 2008), we have had 145 productions, produced 53562 mCi and shipped out 25629 mCi of this isotope to external users. We routinely produce over 400 mCi of this isotope per batch with a specific activity of 14,000 ± 7600 mCi/μmol for distribution to some 12-15 centers each production.
Copyright © 2012 Elsevier Ltd. All rights reserved.

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Year:  2012        PMID: 22516717     DOI: 10.1016/j.apradiso.2012.03.009

Source DB:  PubMed          Journal:  Appl Radiat Isot        ISSN: 0969-8043            Impact factor:   1.513


  19 in total

1.  PET/MRI of Hypoxic Atherosclerosis Using 64Cu-ATSM in a Rabbit Model.

Authors:  Xingyu Nie; Richard Laforest; Andrew Elvington; Gwendalyn J Randolph; Jie Zheng; Tom Voller; Dana R Abendschein; Suzanne E Lapi; Pamela K Woodard
Journal:  J Nucl Med       Date:  2016-07-07       Impact factor: 10.057

2.  Gold Nanoclusters Doped with (64)Cu for CXCR4 Positron Emission Tomography Imaging of Breast Cancer and Metastasis.

Authors:  Yongfeng Zhao; Lisa Detering; Deborah Sultan; Matthew L Cooper; Meng You; Sangho Cho; Stephanie L Meier; Hannah Luehmann; Guorong Sun; Michael Rettig; Farrokh Dehdashti; Karen L Wooley; John F DiPersio; Yongjian Liu
Journal:  ACS Nano       Date:  2016-05-18       Impact factor: 15.881

3.  Design of a multivalent bifunctional chelator for diagnostic 64Cu PET imaging in Alzheimer's disease.

Authors:  Hong-Jun Cho; Truc T Huynh; Buck E Rogers; Liviu M Mirica
Journal:  Proc Natl Acad Sci U S A       Date:  2020-11-24       Impact factor: 11.205

4.  CXCR4-targeted PET imaging using 64Cu-AMD3100 for detection of Waldenström Macroglobulinemia.

Authors:  Barbara Muz; Nilantha Bandara; Cedric Mpoy; Jennifer Sun; Kinan Alhallak; Feda Azab; Buck E Rogers; Abdel Kareem Azab
Journal:  Cancer Biol Ther       Date:  2019-10-01       Impact factor: 4.742

5.  Evaluation of Cu-64 and Ga-68 Radiolabeled Glucagon-Like Peptide-1 Receptor Agonists as PET Tracers for Pancreatic β cell Imaging.

Authors:  Nilantha Bandara; Alex Zheleznyak; Kaavya Cherukuri; David A Griffith; Chris Limberakis; David A Tess; Chen Jianqing; Rikki Waterhouse; Suzanne E Lapi
Journal:  Mol Imaging Biol       Date:  2016-02       Impact factor: 3.488

6.  Optimization of a Pretargeted Strategy for the PET Imaging of Colorectal Carcinoma via the Modulation of Radioligand Pharmacokinetics.

Authors:  Brian M Zeglis; Christian Brand; Dalya Abdel-Atti; Kathryn E Carnazza; Brendon E Cook; Sean Carlin; Thomas Reiner; Jason S Lewis
Journal:  Mol Pharm       Date:  2015-08-31       Impact factor: 4.939

7.  Imaging of hypoxia in mouse atherosclerotic plaques with (64)Cu-ATSM.

Authors:  Xingyu Nie; Gwendalyn J Randolph; Andrew Elvington; Nilantha Bandara; Alexander Zheleznyak; Robert J Gropler; Pamela K Woodard; Suzanne E Lapi
Journal:  Nucl Med Biol       Date:  2016-05-30       Impact factor: 2.408

8.  Multimodal Nanocarrier Probes Reveal Superior Biodistribution Quantification by Isotopic Analysis over Fluorescence.

Authors:  Hongping Deng; Christian J Konopka; Tzu-Wen L Cross; Kelly S Swanson; Lawrence W Dobrucki; Andrew M Smith
Journal:  ACS Nano       Date:  2020-01-07       Impact factor: 15.881

9.  Subtumoral analysis of PRINT nanoparticle distribution reveals targeting variation based on cellular and particle properties.

Authors:  Luke E Roode; Hailey Brighton; Tao Bo; Jillian L Perry; Matthew C Parrott; Farrell Kersey; J Chris Luft; James E Bear; Joseph M DeSimone; Ian J Davis
Journal:  Nanomedicine       Date:  2016-01-07       Impact factor: 5.307

10.  Preclinical Evaluation of an Engineered Single-Chain Fragment Variable-Fragment Crystallizable Targeting Human CD44.

Authors:  Philipp Diebolder; Cedric Mpoy; Jalen Scott; Truc T Huynh; Ryan Fields; Dirk Spitzer; Nilantha Bandara; Buck E Rogers
Journal:  J Nucl Med       Date:  2020-06-08       Impact factor: 11.082

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