Literature DB >> 22516255

Hijacking T cell differentiation: new insights in TLX function in T-ALL.

Bryan King1, Panagiotis Ntziachristos, Iannis Aifantis.   

Abstract

TLX1 and TLX3 are two closely-related homeobox transcriptional repressors frequently misexpressed and translocated in T cell acute lymphoblastic leukemia (T-ALL). In this issue of Cancer Cell, Dadi et al. provide new insights into how these factors are recruited by ETS-1 to the TCRα enhancer and actively repress differentiation.
Copyright © 2012 Elsevier Inc. All rights reserved.

Entities:  

Year:  2012        PMID： 22516255      PMCID： PMC3902167          DOI： 10.1016/j.ccr.2012.03.026

Source DB:  PubMed          Journal:  Cancer Cell        ISSN： 1535-6108            Impact factor:   31.743


  9 in total

Review 1.  Acute promyelocytic leukemia: from treatment to genetics and back.

Authors:  S C Kogan; J M Bishop
Journal:  Oncogene       Date:  1999-09-20       Impact factor: 9.867

2.  Deregulation of a homeobox gene, HOX11, by the t(10;14) in T cell leukemia.

Authors:  M Hatano; C W Roberts; M Minden; W M Crist; S J Korsmeyer
Journal:  Science       Date:  1991-07-05       Impact factor: 47.728

Review 3.  V(D)J recombination: mechanisms of initiation.

Authors:  David G Schatz; Patrick C Swanson
Journal:  Annu Rev Genet       Date:  2011-08-19       Impact factor: 16.830

4.  The BCL11B tumor suppressor is mutated across the major molecular subtypes of T-cell acute lymphoblastic leukemia.

Authors:  Alejandro Gutierrez; Alex Kentsis; Takaomi Sanda; Linda Holmfeldt; Shann-Ching Chen; Jianhua Zhang; Alexei Protopopov; Lynda Chin; Suzanne E Dahlberg; Donna S Neuberg; Lewis B Silverman; Stuart S Winter; Stephen P Hunger; Stephen E Sallan; Shan Zha; Frederick W Alt; James R Downing; Charles G Mullighan; A Thomas Look
Journal:  Blood       Date:  2011-08-30       Impact factor: 22.113

Review 5.  Oncogenic transcription factors in the human acute leukemias.

Authors:  A T Look
Journal:  Science       Date:  1997-11-07       Impact factor: 47.728

6.  PHF6 mutations in T-cell acute lymphoblastic leukemia.

Authors:  Pieter Van Vlierberghe; Teresa Palomero; Hossein Khiabanian; Joni Van der Meulen; Mireia Castillo; Nadine Van Roy; Barbara De Moerloose; Jan Philippé; Sara González-García; María L Toribio; Tom Taghon; Linda Zuurbier; Barbara Cauwelier; Christine J Harrison; Claire Schwab; Markus Pisecker; Sabine Strehl; Anton W Langerak; Jozef Gecz; Edwin Sonneveld; Rob Pieters; Elisabeth Paietta; Jacob M Rowe; Peter H Wiernik; Yves Benoit; Jean Soulier; Bruce Poppe; Xiaopan Yao; Carlos Cordon-Cardo; Jules Meijerink; Raul Rabadan; Frank Speleman; Adolfo Ferrando
Journal:  Nat Genet       Date:  2010-03-14       Impact factor: 38.330

Review 7.  Molecular pathogenesis of T-cell leukaemia and lymphoma.

Authors:  Iannis Aifantis; Elizabeth Raetz; Silvia Buonamici
Journal:  Nat Rev Immunol       Date:  2008-05       Impact factor: 53.106

Review 8.  Accessibility control of variable region gene assembly during T-cell development.

Authors:  B P Sleckman; C H Bassing; C G Bardon; A Okada; B Khor; J C Bories; R Monroe; F W Alt
Journal:  Immunol Rev       Date:  1998-10       Impact factor: 12.988

9.  The TLX1 oncogene drives aneuploidy in T cell transformation.

Authors:  Kim De Keersmaecker; Pedro J Real; Giusy Della Gatta; Teresa Palomero; Maria Luisa Sulis; Valeria Tosello; Pieter Van Vlierberghe; Kelly Barnes; Mireia Castillo; Xavier Sole; Michael Hadler; Jack Lenz; Peter D Aplan; Michelle Kelliher; Barbara L Kee; Pier Paolo Pandolfi; Dietmar Kappes; Fotini Gounari; Howard Petrie; Joni Van der Meulen; Frank Speleman; Elisabeth Paietta; Janis Racevskis; Peter H Wiernik; Jacob M Rowe; Jean Soulier; David Avran; Hélène Cavé; Nicole Dastugue; Susana Raimondi; Jules P P Meijerink; Carlos Cordon-Cardo; Andrea Califano; Adolfo A Ferrando
Journal:  Nat Med       Date:  2010-10-24       Impact factor: 53.440
  9 in total

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