Literature DB >> 22514934

[The role of hematopoietic stem cell transplantation in the treatment of acute radiation injury].

Shuichi Taniguchi1.   

Abstract

The magnitude 9.0 Great East Japan Earthquake on March 11, 2011 brought devastating the world's largest nuclear accidents at the Fukushima Daiichi Nuclear Power Plant. When the mass exposure, hematopoietic tissue, destroyed more quickly with fewer radiation doses compared to other organs. More exposure completely destroys hematopoietic tissues and requires hematopoietic stem cell transplantation. Immunosuppressive therapy as GVHD prophylaxis continues at least 3 months after transplantation and GVHD attacks the same organ as radiation injury in skin, gut and lungs, which makes the treatment so complicated in allogeneic transplantation. If we store autologous stem cells for workers, hematopoietic system can be easily restored. Our conclusion is that we recommend autologous stem cell collection for nuclear power plant workers.

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Year:  2012        PMID: 22514934

Source DB:  PubMed          Journal:  Nihon Rinsho        ISSN: 0047-1852


  2 in total

1.  Twenty years of experience on stem cell transplantation in iran.

Authors:  Ardeshir Ghavamzadeh; Kamran Alimoghaddam; Fatemeh Ghaffari; Roshanak Derakhshandeh; Arash Jalali; Mohammad Jahani
Journal:  Iran Red Crescent Med J       Date:  2013-02-05       Impact factor: 0.611

Review 2.  Hematopoietic Stem Cells and Mesenchymal Stromal Cells in Acute Radiation Syndrome.

Authors:  Liren Qian; Jian Cen
Journal:  Oxid Med Cell Longev       Date:  2020-08-08       Impact factor: 6.543

  2 in total

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