Literature DB >> 22514025

Simple chiral sulfonamide primary amine catalysed highly enantioselective Michael addition of malonates to enones.

Chunhua Luo1, Yu Jin, Da-Ming Du.   

Abstract

A chiral sulfonamide primary amine-organocatalysed, highly enantioselective Michael addition of malonates to enones has been developed. This reaction afforded the corresponding products in excellent yields (up to 99%) and excellent enantioselectivity (up to 99% ee).

Entities:  

Year:  2012        PMID: 22514025     DOI: 10.1039/c2ob07191f

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN: 1477-0520            Impact factor:   3.876


  1 in total

1.  Enantioselective Michael addition of malonates to α,β-unsaturated ketones catalyzed by 1,2-diphenylethanediamine.

Authors:  Wei Wang; Ling Ye; Zhichuan Shi; Zhigang Zhao; Xuefeng Li
Journal:  RSC Adv       Date:  2018-12-12       Impact factor: 4.036

  1 in total

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