Literature DB >> 22512577

Recent updates on biological activities of oxadiazoles.

Rikta Saha1, Omprakash Tanwar, Akranth Marella, M Mumtaz Alam, Mymoona Akhter.   

Abstract

Among the plethora of heterocyclic nucleus discovered, the oxadiazoles have also been explored extensively. The oxadiazole structure has been demonstrated to bear important biological activities such as anti-cancer, antiinflammatory, anti-tuberculosis, anti-malarial and anti-schistosomiasis etc. The presence of oxadiazole motifs in diverse types of compounds proves its importance in the field of medicinal chemistry. This review is complementary to earlier reviews and covers recent updates of various pharmacological aspects of oxadiazoles. To help the reader better know the context for these approaches, a summary of various aspects of background of related topic is presented.

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Year:  2013        PMID: 22512577     DOI: 10.2174/1389557511313070007

Source DB:  PubMed          Journal:  Mini Rev Med Chem        ISSN: 1389-5575            Impact factor:   3.862


  6 in total

1.  Synthesis of Some Benzimidazole Derivatives Bearing 1,3,4-Oxadiazole Moiety as Anticancer Agents.

Authors:  Bereket Mochona; Elizabeth Mazzio; Madhavei Gangapurum; Nelly Mateeva; K K Redda
Journal:  Chem Sci Trans       Date:  2015-04

2.  Synthesis and Cytotoxic Evaluation of Pyrrole Hetarylazoles Containing Benzimidazole/Pyrazolone/1,3,4-Oxadiazole Motifs.

Authors:  Bereket Mochona; Timothy Jackson; DeCoria McCauley; Elizabeth Mazzio; Kinfe K Redda
Journal:  J Heterocycl Chem       Date:  2015-09-18       Impact factor: 2.193

3.  Crystal structure of 2-(4-fluoro-3-methyl-phen-yl)-5-{[(naphthalen-1-yl)-oxy]meth-yl}-1,3,4-oxa-diazole.

Authors:  Muniyappan Govindhan; Kathavarayan Subramanian; Vijayan Viswanathan; Devadasan Velmurugan
Journal:  Acta Crystallogr E Crystallogr Commun       Date:  2015-03-11

4.  The cyanobacterial metabolite nocuolin a is a natural oxadiazine that triggers apoptosis in human cancer cells.

Authors:  Kateřina Voráčová; Jan Hájek; Jan Mareš; Petra Urajová; Marek Kuzma; José Cheel; Andreas Villunger; Alexandra Kapuscik; Marcel Bally; Petr Novák; Martin Kabeláč; Gerhard Krumschnabel; Martin Lukeš; Ludmila Voloshko; Jiří Kopecký; Pavel Hrouzek
Journal:  PLoS One       Date:  2017-03-02       Impact factor: 3.240

Review 5.  Green Synthetic Approach: An Efficient Eco-Friendly Tool for Synthesis of Biologically Active Oxadiazole Derivatives.

Authors:  Bimal Krishna Banik; Biswa Mohan Sahoo; Bera Venkata Varaha Ravi Kumar; Krishna Chandra Panda; Jasma Jena; Manoj Kumar Mahapatra; Preetismita Borah
Journal:  Molecules       Date:  2021-02-22       Impact factor: 4.411

6.  Novel oxadiazole derivatives as potent inhibitors of α-amylase and α-glucosidase enzymes: Synthesis, in vitro evaluation, and molecular docking studies.

Authors:  Asma Bukhari; Humaira Nadeem; Muhammad Imran; Syed Aun Muhammad
Journal:  Iran J Basic Med Sci       Date:  2021-12       Impact factor: 2.699

  6 in total

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