Literature DB >> 22511194

Clonidine utilization trends for Medicaid children.

Esther Y Yoon1, Lisa Cohn, Albert Rocchini, David Kershaw, Sarah J Clark.   

Abstract

OBJECTIVE: To characterize clonidine utilization trends among children. DESIGN/
METHODS: Serial cross-sectional analysis of Michigan Medicaid claims data for children aged 6 to 18 years. The authors identified children with ≥1 clonidine prescription; the authors examined their ICD-9 diagnoses categorized as simple and complex attention deficit hyperactivity disorder (ADHD), non-ADHD mental health disorder, hypertension, or others. Also identified were child demographics and prescribing physician specialty.
RESULTS: From 2003 to 2008, the proportion of children receiving clonidine prescription nearly doubled in all demographics. Across years, the majority of clonidine prescription was for simple and complex ADHD and other mental health disorders. Leading prescribers were psychiatrists followed by general pediatricians and adult primary care physicians.
CONCLUSIONS: Clonidine was used extensively to treat simple and complex ADHD in children although FDA approval for this indication did not occur until 2010. Further study is warranted to better understand clinical outcomes and costs associated with clonidine use for the treatment of children with ADHD.

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Year:  2012        PMID: 22511194      PMCID: PMC3505879          DOI: 10.1177/0009922812441661

Source DB:  PubMed          Journal:  Clin Pediatr (Phila)        ISSN: 0009-9228            Impact factor:   1.168


  11 in total

1.  Herb-drug interactions: potentially important but woefully under-researched.

Authors:  E Ernst
Journal:  Eur J Clin Pharmacol       Date:  2000-11       Impact factor: 2.953

2.  A meta-analysis of clonidine for symptoms of attention-deficit hyperactivity disorder.

Authors:  D F Connor; K E Fletcher; J M Swanson
Journal:  J Am Acad Child Adolesc Psychiatry       Date:  1999-12       Impact factor: 8.829

3.  Recent patterns of medication use in the ambulatory adult population of the United States: the Slone survey.

Authors:  David W Kaufman; Judith P Kelly; Lynn Rosenberg; Theresa E Anderson; Allen A Mitchell
Journal:  JAMA       Date:  2002-01-16       Impact factor: 56.272

4.  Trends in the prescribing of psychotropic medications to preschoolers.

Authors:  J M Zito; D J Safer; S dosReis; J F Gardner; M Boles; F Lynch
Journal:  JAMA       Date:  2000-02-23       Impact factor: 56.272

5.  Clinical practice guideline: treatment of the school-aged child with attention-deficit/hyperactivity disorder.

Authors: 
Journal:  Pediatrics       Date:  2001-10       Impact factor: 7.124

6.  Use of clonidine in children with autism spectrum disorders.

Authors:  Xue Ming; Emily Gordon; Ning Kang; George C Wagner
Journal:  Brain Dev       Date:  2008-02-15       Impact factor: 1.961

7.  Assessment of potential drug interactions in patients with epilepsy: impact of age and sex.

Authors:  Barry E Gidal; Jacqueline A French; Patricia Grossman; Gwénaël Le Teuff
Journal:  Neurology       Date:  2009-02-03       Impact factor: 9.910

8.  Off-label utilization of antihypertensive medications in children.

Authors:  Esther Y Yoon; Kevin J Dombkowski; Albert Rocchini; Jen-Jar Lin; Matthew M Davis
Journal:  Ambul Pediatr       Date:  2007 Jul-Aug

9.  Trends in the prevalence of chronic medication use in children: 2002-2005.

Authors:  Emily R Cox; Donna R Halloran; Sharon M Homan; Sherry Welliver; Douglas E Mager
Journal:  Pediatrics       Date:  2008-11       Impact factor: 7.124

10.  Trends in medication treatment for ADHD.

Authors:  Lon Castle; Ronald E Aubert; Robert R Verbrugge; Mona Khalid; Robert S Epstein
Journal:  J Atten Disord       Date:  2007-05       Impact factor: 3.256

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  2 in total

1.  Poisonings Associated with Intubation: US National Poison Data System Exposures 2000-2013.

Authors:  G A Beauchamp; S L Giffin; B Z Horowitz; A L Laurie; R Fu; R G Hendrickson
Journal:  J Med Toxicol       Date:  2016-06

2.  Hypertensive Crisis in a Pediatric Patient Experiencing Clonidine Withdrawal.

Authors:  Can Cao; Matthew L Lorenz; Phillip Sojka; Allison W Brindle; Lisa Swartz Topor
Journal:  Case Rep Pediatr       Date:  2022-03-22
  2 in total

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