Literature DB >> 22508724

Emerging insights into the molecular and cellular basis of glioblastoma.

Gavin P Dunn1, Mikael L Rinne, Jill Wykosky, Giannicola Genovese, Steven N Quayle, Ian F Dunn, Pankaj K Agarwalla, Milan G Chheda, Benito Campos, Alan Wang, Cameron Brennan, Keith L Ligon, Frank Furnari, Webster K Cavenee, Ronald A Depinho, Lynda Chin, William C Hahn.   

Abstract

Glioblastoma is both the most common and lethal primary malignant brain tumor. Extensive multiplatform genomic characterization has provided a higher-resolution picture of the molecular alterations underlying this disease. These studies provide the emerging view that "glioblastoma" represents several histologically similar yet molecularly heterogeneous diseases, which influences taxonomic classification systems, prognosis, and therapeutic decisions.

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Mesh：

Year:  2012        PMID： 22508724      PMCID： PMC3337451          DOI： 10.1101/gad.187922.112

Source DB:  PubMed          Journal:  Genes Dev        ISSN： 0890-9369            Impact factor:   11.361


  354 in total

1.  Glial progenitors in adult white matter are driven to form malignant gliomas by platelet-derived growth factor-expressing retroviruses.

Authors:  Marcela Assanah; Richard Lochhead; Alfred Ogden; Jeffrey Bruce; James Goldman; Peter Canoll
Journal:  J Neurosci       Date:  2006-06-21       Impact factor: 6.167

2.  A multigene predictor of outcome in glioblastoma.

Authors:  Howard Colman; Li Zhang; Erik P Sulman; J Matthew McDonald; Nasrin Latif Shooshtari; Andreana Rivera; Sonya Popoff; Catherine L Nutt; David N Louis; J Gregory Cairncross; Mark R Gilbert; Heidi S Phillips; Minesh P Mehta; Arnab Chakravarti; Christopher E Pelloski; Krishna Bhat; Burt G Feuerstein; Robert B Jenkins; Ken Aldape
Journal:  Neuro Oncol       Date:  2009-10-20       Impact factor: 12.300

3.  Nuclear PTEN regulates the APC-CDH1 tumor-suppressive complex in a phosphatase-independent manner.

Authors:  Min Sup Song; Arkaitz Carracedo; Leonardo Salmena; Su Jung Song; Ainara Egia; Marcos Malumbres; Pier Paolo Pandolfi
Journal:  Cell       Date:  2011-01-21       Impact factor: 41.582

4.  PIK3CA alterations in primary (de novo) and secondary glioblastomas.

Authors:  Daisuke Kita; Yasuhiro Yonekawa; Michael Weller; Hiroko Ohgaki
Journal:  Acta Neuropathol       Date:  2007-01-18       Impact factor: 17.088

5.  Cooperativity within and among Pten, p53, and Rb pathways induces high-grade astrocytoma in adult brain.

Authors:  Lionel M L Chow; Raelene Endersby; Xiaoyan Zhu; Sherri Rankin; Chunxu Qu; Junyuan Zhang; Alberto Broniscer; David W Ellison; Suzanne J Baker
Journal:  Cancer Cell       Date:  2011-03-08       Impact factor: 31.743

6.  TGF-beta IL-6 axis mediates selective and adaptive mechanisms of resistance to molecular targeted therapy in lung cancer.

Authors:  Zhan Yao; Silvia Fenoglio; Ding Cheng Gao; Matthew Camiolo; Brendon Stiles; Trine Lindsted; Michaela Schlederer; Chris Johns; Nasser Altorki; Vivek Mittal; Lukas Kenner; Raffaella Sordella
Journal:  Proc Natl Acad Sci U S A       Date:  2010-08-16       Impact factor: 11.205

7.  A network model of a cooperative genetic landscape in brain tumors.

Authors:  Markus Bredel; Denise M Scholtens; Griffith R Harsh; Claudia Bredel; James P Chandler; Jaclyn J Renfrow; Ajay K Yadav; Hannes Vogel; Adrienne C Scheck; Robert Tibshirani; Branimir I Sikic
Journal:  JAMA       Date:  2009-07-15       Impact factor: 56.272

Review 8.  Using mice to decipher the molecular genetics of brain tumors.

Authors:  Göran Hesselager; Eric C Holland
Journal:  Neurosurgery       Date:  2003-09       Impact factor: 4.654

9.  Genomic changes in progression of low-grade gliomas.

Authors:  Ahmed Idbaih; Rosana Carvalho Silva; Emmanuelle Crinière; Yannick Marie; Catherine Carpentier; Blandine Boisselier; Sophie Taillibert; Audrey Rousseau; Karima Mokhtari; François Ducray; Joelle Thillet; Marc Sanson; Khê Hoang-Xuan; Jean-Yves Delattre
Journal:  J Neurooncol       Date:  2008-07-11       Impact factor: 4.130

10.  PTEN, NHERF1 and PHLPP form a tumor suppressor network that is disabled in glioblastoma.

Authors:  J R Molina; N K Agarwal; F C Morales; Y Hayashi; K D Aldape; G Cote; M-M Georgescu
Journal:  Oncogene       Date:  2011-08-01       Impact factor: 9.867
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  264 in total

1.  Collateral Lethality: A new therapeutic strategy in oncology.

Authors:  Florian L Muller; Elisa A Aquilanti; Ronald A DePinho
Journal:  Trends Cancer       Date:  2015-11-01

2.  Epigenetic Regulation of ZBTB18 Promotes Glioblastoma Progression.

Authors:  Vita Fedele; Fangping Dai; Anie P Masilamani; Dieter H Heiland; Eva Kling; Ana M Gätjens-Sanchez; Roberto Ferrarese; Leonardo Platania; Doostkam Soroush; Hyunsoo Kim; Sven Nelander; Astrid Weyerbrock; Marco Prinz; Andrea Califano; Antonio Iavarone; Markus Bredel; Maria S Carro
Journal:  Mol Cancer Res       Date:  2017-05-16       Impact factor: 5.852

3.  p53 and NF 1 loss plays distinct but complementary roles in glioma initiation and progression.

Authors:  Phillippe P Gonzalez; Jungeun Kim; Rui Pedro Galvao; Nichola Cruickshanks; Roger Abounader; Hui Zong
Journal:  Glia       Date:  2018-02-02       Impact factor: 7.452

4.  Micro-editing mistake translates into a devastating brain tumor.

Authors:  Dan Dominissini; Ninette Amariglio; Gideon Rechavi
Journal:  J Clin Invest       Date:  2012-10-24       Impact factor: 14.808

5.  Proinvasive extracellular matrix remodeling in tumor microenvironment in response to radiation.

Authors:  Ki-Chun Yoo; Yongjoon Suh; Yoojeong An; Hae-June Lee; Ye Ji Jeong; Nizam Uddin; Yan-Hong Cui; Tae-Hoon Roh; Jin-Kyoung Shim; Jong Hee Chang; Jong Bae Park; Min-Jung Kim; In-Gyu Kim; Seok-Gu Kang; Su-Jae Lee
Journal:  Oncogene       Date:  2018-03-21       Impact factor: 9.867

6.  Suppression of microRNA-9 by mutant EGFR signaling upregulates FOXP1 to enhance glioblastoma tumorigenicity.

Authors:  German G Gomez; Stefano Volinia; Carlo M Croce; Ciro Zanca; Ming Li; Ryan Emnett; David H Gutmann; Cameron W Brennan; Frank B Furnari; Webster K Cavenee
Journal:  Cancer Res       Date:  2014-01-16       Impact factor: 12.701

Review 7.  Nexus of signaling and endocytosis in oncogenesis driven by non-small cell lung cancer-associated epidermal growth factor receptor mutants.

Authors:  Byung Min Chung; Eric Tom; Neha Zutshi; Timothy Alan Bielecki; Vimla Band; Hamid Band
Journal:  World J Clin Oncol       Date:  2014-12-10

8.  A glioma classification scheme based on coexpression modules of EGFR and PDGFRA.

Authors:  Yingyu Sun; Wei Zhang; Dongfeng Chen; Yuhong Lv; Junxiong Zheng; Henrik Lilljebjörn; Liang Ran; Zhaoshi Bao; Charlotte Soneson; Hans Olov Sjögren; Leif G Salford; Jianguang Ji; Pim J French; Thoas Fioretos; Tao Jiang; Xiaolong Fan
Journal:  Proc Natl Acad Sci U S A       Date:  2014-02-18       Impact factor: 11.205

9.  The Ig superfamily protein PTGFRN coordinates survival signaling in glioblastoma multiforme.

Authors:  Brittany Aguila; Adina Brett Morris; Raffaella Spina; Eli Bar; Julie Schraner; Robert Vinkler; Jason W Sohn; Scott M Welford
Journal:  Cancer Lett       Date:  2019-08-01       Impact factor: 8.679

10.  Systemic anticancer neural stem cells in combination with a cardiac glycoside for glioblastoma therapy.

Authors:  Jian Teng; Seyedali Hejazi; Christian E Badr; Bakhos A Tannous
Journal:  Stem Cells       Date:  2014-08       Impact factor: 6.277
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