Literature DB >> 22508278

Lewy pathology and neurodegeneration in premotor Parkinson's disease.

Kelly Del Tredici1, Heiko Braak.   

Abstract

The foremost motor manifestations of Parkinson's disease are resting tremor, cogwheel rigidity, hypokinesia/bradykinesia, and postural instability. Epidemiological and clinical data reveal that a wide variety of additional complaints (nonmotor symptoms), also considerably impar patients' quality of life parallel to the chronic-progressive neurodegenerative disorder. This article reviews the neuropathology and anatomy of Lewy pathology-related neurodegeneration in relation to selected nonmotro and prodromal dysfunctions.
Copyright © 2012 Movement Disorder Society.

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Year:  2012        PMID： 22508278     DOI： 10.1002/mds.24921

Source DB:  PubMed          Journal:  Mov Disord        ISSN： 0885-3185            Impact factor:   10.338


  54 in total

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Review 8.  The pathology roadmap in Parkinson disease.

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Review 9.  Mesenchymal Stromal Cell Therapies for Neurodegenerative Diseases.

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Review 10.  Is there a need to redefine Parkinson's disease?

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