Literature DB >> 2250717

A yeast mitochondrial outer membrane protein essential for protein import and cell viability.

K P Baker1, A Schaniel, D Vestweber, G Schatz.   

Abstract

The gene encoding ISP42, an integral outermembrane protein located at the yeast mitochondrial protein import site was cloned, sequenced and modified. Yeast cells depleted of ISP42 accumulate uncleaved mitochondrial precursor proteins and then die. ISP42 is the first mitochondrial membrane protein shown to be indispensable for protein import and cell viability.

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Year:  1990        PMID： 2250717     DOI： 10.1038/348605a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  60 in total

1.  Uncoupling of transfer of the presequence and unfolding of the mature domain in precursor translocation across the mitochondrial outer membrane.

Authors:  T Kanamori; S Nishikawa; M Nakai; I Shin; P G Schultz; T Endo
Journal:  Proc Natl Acad Sci U S A       Date:  1999-03-30       Impact factor: 11.205

Review 2.  Signals and receptors--the translocation machinery on the mitochondrial surface.

Authors:  E Schleiff
Journal:  J Bioenerg Biomembr       Date:  2000-02       Impact factor: 2.945

3.  Identification of a 45-kDa protein at the protein import site of the yeast mitochondrial inner membrane.

Authors:  P E Scherer; U C Manning-Krieg; P Jenö; G Schatz; M Horst
Journal:  Proc Natl Acad Sci U S A       Date:  1992-12-15       Impact factor: 11.205

Review 4.  Targeting proteins to mitochondria: a current overview.

Authors:  L A Glover; J G Lindsay
Journal:  Biochem J       Date:  1992-06-15       Impact factor: 3.857

Review 5.  Targeting and translocation of mitochondrial precursor proteins.

Authors:  P Keil; J Schlossmann; N Pfanner
Journal:  Antonie Van Leeuwenhoek       Date:  1992-02       Impact factor: 2.271

6.  MAS5, a yeast homolog of DnaJ involved in mitochondrial protein import.

Authors:  D P Atencio; M P Yaffe
Journal:  Mol Cell Biol       Date:  1992-01       Impact factor: 4.272

7.  The precursor of PsaD assembles into the photosystem I complex in two steps.

Authors:  L Minai; Y Cohen; P R Chitnis; R Nechushtai
Journal:  Proc Natl Acad Sci U S A       Date:  1996-06-25       Impact factor: 11.205

8.  Assembly of deletion mutants of the Rieske iron-sulfur protein into the cytochrome bc1 complex of yeast mitochondria.

Authors:  R S Ramabadran; S Japa; D S Beattie
Journal:  J Bioenerg Biomembr       Date:  1997-02       Impact factor: 2.945

Review 9.  The mitochondrial protein import pathway: are precursors imported through membrane channels?

Authors:  R E Jensen; K W Kinnally
Journal:  J Bioenerg Biomembr       Date:  1997-02       Impact factor: 2.945

10.  RPM2, independently of its mitochondrial RNase P function, suppresses an ISP42 mutant defective in mitochondrial import and is essential for normal growth.

Authors:  C K Kassenbrock; G J Gao; K R Groom; P Sulo; M G Douglas; N C Martin
Journal:  Mol Cell Biol       Date:  1995-09       Impact factor: 4.272
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