Literature DB >> 22507063

Osteoporosis and osteopenia: implications for periodontal and implant therapy.

Joan Otomo-Corgel.   

Abstract

How does low bone mineral density alter treatment decisions? Osteoporosis and osteopenia are major health care issues that may impact on periodontal and implant therapy. Because of the prevalence of osteoporosis, understanding its etiology and the current treatment regimens for patients with low bone mineral density is essential for dental professionals. Millions of patients are now taking medications for the treatment of osteoporosis, and periodontists should be aware of the many medication options that are prescribed. The most frequently prescribed drugs are the bisphosphonates. It is important to be aware that bisphosphonates are not all the same, and patient responses to treatment may vary depending on which bisphosphonates they are taking. Due to recent concerns about bisphosphonate-induced osteonecrosis of the jaw, this paper provides guidance to help the clinician regarding decision-making about preventive and interventional dental treatment when their patient has been prescribed a bisphosphonate. An understanding of current bisphosphonates, their uses, their structural differences and their intended actions helps to improve clinical decision-making. Current knowledge regarding the effects of osteoporosis/osteopenia on periodontal diseases and alveolar bone loss is inconclusive. It is certainly clear that bisphosphonates are not indicated as an adjunctive treatment as part of periodontal therapy because of the risk of osteonecrosis. Regarding implant placement, there are no convincing data that dental implant placement is contraindicated in the osteoporotic patient. However, patients should understand the small risk of compromised bone healing following implant placement if the patient has been taking bisphosphonates. Due to the risks of osteonecrosis, dental clinicians should work closely with their medical colleagues prior to the physician prescribing oral bisphosphonates. Ideally, optimal periodontal and dental health should be established before the patient commences bisphosphonate therapy.
© 2012 John Wiley & Sons A/S.

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Year:  2012        PMID: 22507063     DOI: 10.1111/j.1600-0757.2011.00435.x

Source DB:  PubMed          Journal:  Periodontol 2000        ISSN: 0906-6713            Impact factor:   7.589


  9 in total

1.  Osteoporotic Changes in the Periodontium Impair Alveolar Bone Healing.

Authors:  M Arioka; X Zhang; Z Li; U S Tulu; Y Liu; L Wang; X Yuan; J A Helms
Journal:  J Dent Res       Date:  2019-01-09       Impact factor: 6.116

2.  The impact of premature birth on the mandibular cortical bone of children.

Authors:  L Paulsson-Björnsson; J Adams; L Bondemark; H Devlin; K Horner; C Lindh
Journal:  Osteoporos Int       Date:  2014-09-30       Impact factor: 4.507

3.  Antiresorptive therapy and dental implant survival: an up to 20-year retrospective cohort study in women.

Authors:  Yu-Chi Cheng; Rolf Ewers; Katherine Morgan; Muneki Hirayama; Laura Murcko; John Morgan; Edmara T P Bergamo; Estevam A Bonfante
Journal:  Clin Oral Investig       Date:  2022-08-24       Impact factor: 3.606

4.  Plasma sprayed cerium oxide coating inhibits H2O2-induced oxidative stress and supports cell viability.

Authors:  Kai Li; Youtao Xie; Mingyu You; Liping Huang; Xuebin Zheng
Journal:  J Mater Sci Mater Med       Date:  2016-04-18       Impact factor: 3.896

5.  Texturized P(VDF-TrFE)/BT membrane enhances bone neoformation in calvaria defects regardless of the association with photobiomodulation therapy in ovariectomized rats.

Authors:  Fernanda Cristina Toloi Rufato; Luiz Gustavo de Sousa; Priscilla Hakime Scalize; Rossano Gimenes; Isabela Hallak Regalo; Adalberto Luiz Rosa; Marcio Mateus Beloti; Fabíola Singaretti de Oliveira; Karina Fittipaldi Bombonato-Prado; Simone Cecilio Hallak Regalo; Selma Siéssere
Journal:  Clin Oral Investig       Date:  2021-08-09       Impact factor: 3.573

Review 6.  Bisphosphonate treatment and dental implants: A systematic review.

Authors:  N-R de-Freitas; L-B Lima; M-B de-Moura; C-C-F Veloso-Guedes; P-C Simamoto-Júnior; D de-Magalhães
Journal:  Med Oral Patol Oral Cir Bucal       Date:  2016-09-01

Review 7.  Alveolar bone loss in osteoporosis: a loaded and cellular affair?

Authors:  Grethe Jonasson; Marianne Rythén
Journal:  Clin Cosmet Investig Dent       Date:  2016-07-13

8.  Intraosseous Injection of Calcium Phosphate Polymer-Induced Liquid Precursor Increases Bone Density and Improves Early Implant Osseointegration in Ovariectomized Rats.

Authors:  Yanyan Zhou; Zihe Hu; Mingjie Ge; Wenjing Jin; Ruikang Tang; Qi Li; Weijian Xu; Jue Shi; Zhijian Xie
Journal:  Int J Nanomedicine       Date:  2021-09-10

9.  Attitudes and perceptions of GPs and community pharmacists towards their role in the prevention of bisphosphonate-related osteonecrosis of the jaw: a qualitative study in the North East of England.

Authors:  Andrew Sturrock; Philip M Preshaw; Catherine Hayes; Scott Wilkes
Journal:  BMJ Open       Date:  2017-09-29       Impact factor: 2.692

  9 in total

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