Literature DB >> 22506265

A TEMPO-conjugated fluorescent probe for monitoring mitochondrial redox reactions.

Shota Hirosawa1, Satoshi Arai, Shinji Takeoka.   

Abstract

We report a mitochondrial targeted redox probe (MitoRP) that comprises a nitroxide radical (TEMPO) moiety and coumarin 343. Using isolated mitochondria in the presence/absence of substrates and inhibitors of oxidative phosphorylation, we demonstrated that MitoRP is a useful probe to monitor the electron flow associated with complex I. This journal is © The Royal Society of Chemistry 2012

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Year:  2012        PMID： 22506265     DOI： 10.1039/c2cc30603d

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  4 in total

Review 1.  Mitochondrially targeted fluorescent redox sensors.

Authors:  Kylie Yang; Jacek L Kolanowski; Elizabeth J New
Journal:  Interface Focus       Date:  2017-04-06       Impact factor: 3.906

Review 2.  State-of-the-art: functional fluorescent probes for bioimaging and pharmacological research.

Authors:  Lu Lu; Zhou-Yue Wu; Xin Li; Feng Han
Journal:  Acta Pharmacol Sin       Date:  2018-11-28       Impact factor: 6.150

Review 3.  Small-molecule luminescent probes for the detection of cellular oxidizing and nitrating species.

Authors:  Jacek Zielonka; Balaraman Kalyanaraman
Journal:  Free Radic Biol Med       Date:  2018-03-19       Impact factor: 7.376

4.  In vivo fluorescence bioimaging of ascorbic acid in mice: Development of an efficient probe consisting of phthalocyanine, TEMPO, and albumin.

Authors:  Takanori Yokoi; Takayuki Otani; Kazuyuki Ishii
Journal:  Sci Rep       Date:  2018-01-24       Impact factor: 4.379
  4 in total

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