Literature DB >> 22503327

Analysis of blood-based gene expression signature in first-episode psychosis.

Jimmy Lee1, Liang-Kee Goh, Gengbo Chen, Swapna Verma, Chay-Hoon Tan, Tih-Shih Lee.   

Abstract

Blood-based transcriptomic signature in psychosis is an alternative to a brain-based signature. In this study, we profiled whole-blood RNA from 26 patients with first-episode psychosis, and 26 matching controls. We identified a 400-gene signature that classified patients from controls accurately and tested the robustness using other modelling methods.
Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

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Year:  2012        PMID： 22503327     DOI： 10.1016/j.psychres.2012.03.021

Source DB:  PubMed          Journal:  Psychiatry Res        ISSN： 0165-1781            Impact factor:   3.222


  10 in total

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2.  An investigation of how normalisation and local modelling techniques confound machine learning performance in a mental health study.

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5.  Candidate gene networks and blood biomarkers of methamphetamine-associated psychosis: an integrative RNA-sequencing report.

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6.  Predicting Autism Spectrum Disorder Using Blood-based Gene Expression Signatures and Machine Learning.

Authors:  Dong Hoon Oh; Il Bin Kim; Seok Hyeon Kim; Dong Hyun Ahn
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7.  GAD1 Gene Expression in Blood of Patients with First-Episode Psychosis.

Authors:  Jie Yin Yee; Milawaty Nurjono; Stephanie Ruth Teo; Tih-Shih Lee; Jimmy Lee
Journal:  PLoS One       Date:  2017-01-25       Impact factor: 3.240

8.  Profile of the Nicotinic Cholinergic Receptor Alpha 7 Subunit Gene Expression is Associated with Response to Varenicline Treatment.

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Journal:  Genes (Basel)       Date:  2020-07-06       Impact factor: 4.096

9.  Can Peripheral Blood-Derived Gene Expressions Characterize Individuals at Ultra-high Risk for Psychosis?

Authors:  Wilson Wen Bin Goh; Judy Chia-Ghee Sng; Jie Yin Yee; Yuen Mei See; Tih-Shih Lee; Limsoon Wong; Jimmy Lee
Journal:  Comput Psychiatr       Date:  2017-12-01

10.  Differential gene expression analysis in blood of first episode psychosis patients.

Authors:  Daniel J Leirer; Conrad O Iyegbe; Marta Di Forti; Hamel Patel; Elena Carra; Sara Fraietta; Marco Colizzi; Valeria Mondelli; Diego Quattrone; John Lally; Olesya Ajnakina; Sang Hyuck Lee; Charles J Curtis; Gerome Breen; Carmine Pariante; Katherine Aitchison; Paola Dazzan; Robin M Murray; Richard J B Dobson; Stephen J Newhouse
Journal:  Schizophr Res       Date:  2019-05-19       Impact factor: 4.939
  10 in total

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