Literature DB >> 22499466

Probiotics in the gastrointestinal diseases of the elderly.

G Malaguarnera1, F Leggio, M Vacante, M Motta, M Giordano, A Bondi, F Basile, S Mastrojeni, A Mistretta, M Malaguarnera, M A Toscano, M Salmeri.   

Abstract

Changes of the gut microflora in elderly appear to involve a reduction in numbers of healthy bacteria (lactobacilli and bifidobacteria) and an increase in numbers of potentially pathogenic species. These changes are generally described as gastrointestinal disorders and infections. This review analyses benefits of probiotics in old people, with particular interesting for the latest researches relevant to elderly people, e.g. trials examining enteric infections, antibiotic-associated diarrhea and Clostridium difficile associated diarrhea, functional bowel problems (constipation and irritable bowel syndrome), inflammatory bowel diseases, stimulation of the immune system and prevention of cancer. A growing number of researches indicates that some probiotic strains may help to maintain the health in old people, suggesting both health and cost-saving benefits in offering fermented dairy products. These benefits include: establishment of balanced intestinal microflora; improving colonization resistance and or prevention of diarrhea; reduction of fecal enzymes; reduction of serum cholesterol; reduction of potential mutagenes; reduction of lactose intolerance; synthesis of vitamins; predigestion of proteins.

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Year:  2012        PMID: 22499466     DOI: 10.1007/s12603-011-0357-1

Source DB:  PubMed          Journal:  J Nutr Health Aging        ISSN: 1279-7707            Impact factor:   4.075


  101 in total

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Review 2.  Probiotic properties of lactic-acid bacteria: plenty of scope for fundamental R & D.

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Journal:  J Proteome Res       Date:  2005 Sep-Oct       Impact factor: 4.466

Review 4.  The role of lactic acid bacteria in colon cancer prevention.

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Journal:  Scand J Gastroenterol       Date:  1995-06       Impact factor: 2.423

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Journal:  Asia Pac J Clin Nutr       Date:  1996-03       Impact factor: 1.662

6.  Highly efficient gluten degradation with a newly identified prolyl endoprotease: implications for celiac disease.

Authors:  Dariusz Stepniak; Liesbeth Spaenij-Dekking; Cristina Mitea; Martine Moester; Arnoud de Ru; Renee Baak-Pablo; Peter van Veelen; Luppo Edens; Frits Koning
Journal:  Am J Physiol Gastrointest Liver Physiol       Date:  2006-05-11       Impact factor: 4.052

7.  Prophylaxis of pouchitis onset with probiotic therapy: a double-blind, placebo-controlled trial.

Authors:  Paolo Gionchetti; Fernando Rizzello; Ulf Helwig; Alessandro Venturi; Karen Manon Lammers; Patrizia Brigidi; Beatrice Vitali; Gilberto Poggioli; Mario Miglioli; Massimo Campieri
Journal:  Gastroenterology       Date:  2003-05       Impact factor: 22.682

Review 8.  The role of immunity in elderly cancer.

Authors:  Lucia Malaguarnera; Erika Cristaldi; Mariano Malaguarnera
Journal:  Crit Rev Oncol Hematol       Date:  2009-07-04       Impact factor: 6.312

9.  Prevalence of Celiac disease among children in Finland.

Authors:  Markku Mäki; Kirsi Mustalahti; Jorma Kokkonen; Petri Kulmala; Mila Haapalahti; Tuomo Karttunen; Jorma Ilonen; Kaija Laurila; Ingrid Dahlbom; Tony Hansson; Peter Höpfl; Mikael Knip
Journal:  N Engl J Med       Date:  2003-06-19       Impact factor: 91.245

10.  Binding of mutagenic heterocyclic amines by intestinal and lactic acid bacteria.

Authors:  K Orrhage; E Sillerström; J A Gustafsson; C E Nord; J Rafter
Journal:  Mutat Res       Date:  1994-12-01       Impact factor: 2.433

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  29 in total

Review 1.  Contemporary meta-analysis of short-term probiotic consumption on gastrointestinal transit.

Authors:  Larry E Miller; Angela K Zimmermann; Arthur C Ouwehand
Journal:  World J Gastroenterol       Date:  2016-06-07       Impact factor: 5.742

Review 2.  Compositional dynamics of the human intestinal microbiota with aging: implications for health.

Authors:  B Lakshminarayanan; C Stanton; P W O'Toole; R P Ross
Journal:  J Nutr Health Aging       Date:  2014-11       Impact factor: 4.075

Review 3.  Oral anticancer drugs: mechanisms of low bioavailability and strategies for improvement.

Authors:  Frederik E Stuurman; Bastiaan Nuijen; Jos H Beijnen; Jan H M Schellens
Journal:  Clin Pharmacokinet       Date:  2013-06       Impact factor: 6.447

Review 4.  Probiotic bacteria as modulators of cellular senescence: emerging concepts and opportunities.

Authors:  Rohit Sharma; Yogendra Padwad
Journal:  Gut Microbes       Date:  2019-12-10

5.  Evolving Roles of Probiotics in Cancer Prophylaxis and Therapy.

Authors:  Seema Patel; Arun Goyal
Journal:  Probiotics Antimicrob Proteins       Date:  2013-03       Impact factor: 4.609

Review 6.  Gut microbiota in alcoholic liver disease: pathogenetic role and therapeutic perspectives.

Authors:  Giulia Malaguarnera; Maria Giordano; Giuseppe Nunnari; Gaetano Bertino; Michele Malaguarnera
Journal:  World J Gastroenterol       Date:  2014-11-28       Impact factor: 5.742

Review 7.  Probiotic supplementation decreases intestinal transit time: meta-analysis of randomized controlled trials.

Authors:  Larry E Miller; Arthur C Ouwehand
Journal:  World J Gastroenterol       Date:  2013-08-07       Impact factor: 5.742

Review 8.  Probiotics against neoplastic transformation of gastric mucosa: effects on cell proliferation and polyamine metabolism.

Authors:  Francesco Russo; Michele Linsalata; Antonella Orlando
Journal:  World J Gastroenterol       Date:  2014-10-07       Impact factor: 5.742

9.  Analysis of fecal microbiota in patients with functional constipation undergoing treatment with synbiotics.

Authors:  Lin Sheng Huang; Cheng Kong; Ren Yuan Gao; Xuebing Yan; Hong Jing Yu; Bin Wen; Qi Zhu; Tong Yi Shen; Zhen Liang Sun; Huan Long Qin
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2018-01-16       Impact factor: 3.267

10.  Use of Antibiotics and Probiotics Reduces the Risk of Metachronous Gastric Cancer after Endoscopic Resection.

Authors:  Junya Arai; Ryota Niikura; Yoku Hayakawa; Takuya Kawahara; Tetsuro Honda; Kenkei Hasatani; Naohiro Yoshida; Tsutomu Nishida; Tetsuya Sumiyoshi; Shu Kiyotoki; Takashi Ikeya; Masahiro Arai; Nobumi Suzuki; Yosuke Tsuji; Atsuo Yamada; Takashi Kawai; Kazuhiko Koike
Journal:  Biology (Basel)       Date:  2021-05-22
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