Literature DB >> 22499398

A highly enantioselective catalytic Strecker reaction of cyclic (Z)-aldimines.

You-Dong Shao1, Shi-Kai Tian.   

Abstract

A range of 3H-indoles and 2H-benzo[b][1,4]thiazines smoothly undergo asymmetric Strecker reaction with ethyl cyanoformate in the presence of a Cinchona alkaloid-based thiourea catalyst at 10 °C to give structurally diverse nitrogen-containing heterocycles in good to excellent yields and with excellent ee. This journal is © The Royal Society of Chemistry 2012

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Year:  2012        PMID: 22499398     DOI: 10.1039/c2cc31001e

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  2 in total

1.  Automated and Accelerated Synthesis of Indole Derivatives on a Nano-Scale.

Authors:  Shabnam Shaabani; Ruixue Xu; Maryam Ahmadianmoghaddam; Li Gao; Martin Stahorsky; Joe Olechno; Richard Ellson; Michael Kossenjans; Victoria Helan; Alexander Dömling
Journal:  Green Chem       Date:  2018-12-21       Impact factor: 10.182

2.  From Heteroaromatic Acids and Imines to Azaspirocycles: Stereoselective Synthesis and 3D Shape Analysis.

Authors:  Sarah J Chambers; Graeme Coulthard; William P Unsworth; Peter O'Brien; Richard J K Taylor
Journal:  Chemistry       Date:  2016-03-23       Impact factor: 5.236

  2 in total

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