INTRODUCTION: This report is a meta-analysis of the human muscle architecture literature that analyzes the number of muscles, number of subjects, and muscle fiber length coefficient of variation (CV) by body region. METHODS: Muscle fiber length data are used to make recommendations for dissection-based architectural study sample sizes. RESULTS: An average of 9 ± 10 (mean ± SD) muscles and an average of 9 ± 5 subjects were reported in the 26 studies considered. Across all studies, average fiber length CV was highly variable (18% ± 5%). This shows that sample sizes required to achieve adequate power varies by anatomical region. CONCLUSIONS: Studies involving muscle architecture should consider regional variability and effect size and determine sample size accordingly.
INTRODUCTION: This report is a meta-analysis of the human muscle architecture literature that analyzes the number of muscles, number of subjects, and muscle fiber length coefficient of variation (CV) by body region. METHODS: Muscle fiber length data are used to make recommendations for dissection-based architectural study sample sizes. RESULTS: An average of 9 ± 10 (mean ± SD) muscles and an average of 9 ± 5 subjects were reported in the 26 studies considered. Across all studies, average fiber length CV was highly variable (18% ± 5%). This shows that sample sizes required to achieve adequate power varies by anatomical region. CONCLUSIONS: Studies involving muscle architecture should consider regional variability and effect size and determine sample size accordingly.
Authors: Gilad J Regev; Choll W Kim; Akihito Tomiya; Yu Po Lee; Hossein Ghofrani; Steven R Garfin; Richard L Lieber; Samuel R Ward Journal: Spine (Phila Pa 1976) Date: 2011-12-15 Impact factor: 3.468
Authors: Marianna Alperin; Mark Cook; Lori J Tuttle; Mary C Esparza; Richard L Lieber Journal: Am J Obstet Gynecol Date: 2016-03-05 Impact factor: 8.661