Literature DB >> 22498879

CO2 gas induced drug release from pH-sensitive liposome to circumvent doxorubicin resistant cells.

Juan Liu1, Huili Ma, Tuo Wei, Xing-Jie Liang.   

Abstract

A novel pH-sensitive liposome encapsulating doxorubicin was prepared by a NH(4)HCO(3) gradient method. The liposomes were able to release the drug at pH 5.0 by the production of CO(2) gas. More importantly, the drug-loaded liposome effectively circumvented the breast cancer cells resistant to doxorubicin. This journal is © The Royal Society of Chemistry 2012

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Year:  2012        PMID： 22498879     DOI： 10.1039/c2cc31697h

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  12 in total

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Journal:  Theranostics       Date:  2017-01-07       Impact factor: 11.556

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Review 10.  Tumor microenvironment responsive drug delivery systems.

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Journal:  Asian J Pharm Sci       Date:  2019-09-26       Impact factor: 6.598
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