SCOPE: The main objectives of this study were to estimate dietary fumonisin exposure and nutrient intake in a group of patients diagnosed with celiac disease compared to non-celiac subjects. METHODS AND RESULTS: The fumonisin level in 118 frequently consumed corn-based products was determined and dietary habits were recorded using a 7-day weighed food record. Data were then compared to those obtained for a control group. The fumonisin intake in the celiac patients was significantly higher than in controls, with mean values (± SE) of 0.395 ± 0.049 and 0.029 ± 0.006 μg/kg body weight per day, respectively. With regard to nutritional habits, celiac patients showed a preference for a high fat diet, coupled with a high intake of sweets and soft drinks and a low intake of vegetables, iron, calcium and folate. CONCLUSION: These findings may have serious health implications for the celiac population due to the widespread occurrence of fumonisins in most of the widely consumed gluten-free products, leading to continuous exposure to this particular mycotoxin. Moreover, the recorded nutritional quality of the celiac patient's diet raises concerns regarding its long-term adequacy and its potential impact on chronic conditions such as type 2 diabetes and cardiovascular diseases.
SCOPE: The main objectives of this study were to estimate dietary fumonisin exposure and nutrient intake in a group of patients diagnosed with celiac disease compared to non-celiac subjects. METHODS AND RESULTS: The fumonisin level in 118 frequently consumed corn-based products was determined and dietary habits were recorded using a 7-day weighed food record. Data were then compared to those obtained for a control group. The fumonisin intake in the celiac patients was significantly higher than in controls, with mean values (± SE) of 0.395 ± 0.049 and 0.029 ± 0.006 μg/kg body weight per day, respectively. With regard to nutritional habits, celiac patients showed a preference for a high fat diet, coupled with a high intake of sweets and soft drinks and a low intake of vegetables, iron, calcium and folate. CONCLUSION: These findings may have serious health implications for the celiac population due to the widespread occurrence of fumonisins in most of the widely consumed gluten-free products, leading to continuous exposure to this particular mycotoxin. Moreover, the recorded nutritional quality of the celiac patient's diet raises concerns regarding its long-term adequacy and its potential impact on chronic conditions such as type 2 diabetes and cardiovascular diseases.
Authors: Petr Karlovsky; Michele Suman; Franz Berthiller; Johan De Meester; Gerhard Eisenbrand; Irène Perrin; Isabelle P Oswald; Gerrit Speijers; Alessandro Chiodini; Tobias Recker; Pierre Dussort Journal: Mycotoxin Res Date: 2016-08-23 Impact factor: 3.833
Authors: Francisco Cabrera-Chávez; Gimena V A Dezar; Anna P Islas-Zamorano; Jesús G Espinoza-Alderete; Marcela J Vergara-Jiménez; Dalia Magaña-Ordorica; Noé Ontiveros Journal: Nutrients Date: 2017-01-21 Impact factor: 5.717
Authors: Francesco Valitutti; Barbara De Santis; Chiara Maria Trovato; Monica Montuori; Simona Gatti; Salvatore Oliva; Carlo Brera; Carlo Catassi Journal: Nutrients Date: 2018-03-10 Impact factor: 5.717