Literature DB >> 22495252

Portable Biomarker Detection with Magnetic Nanotags.

Drew A Hall1, Shan X Wang, Boris Murmann, Richard S Gaster.   

Abstract

This paper presents a hand-held, portable biosensor platform for quantitative biomarker measurement. By combining magnetic nanoparticle (MNP) tags with giant magnetoresistive (GMR) spin-valve sensors, the hand-held platform achieves highly sensitive (picomolar) and specific biomarker detection in less than 20 minutes. The rapid analysis and potential low cost make this technology ideal for point-of-care (POC) diagnostics. Furthermore, this platform is able to detect multiple biomarkers simultaneously in a single assay, creating a promising diagnostic tool for a vast number of applications.

Entities:  

Year:  2010        PMID: 22495252      PMCID: PMC3321410          DOI: 10.1109/ISCAS.2010.5537639

Source DB:  PubMed          Journal:  Conf Proc (Midwest Symp Circuits Syst)        ISSN: 1548-3746


  8 in total

1.  An integrated and sensitive detection platform for magneto-resistive biosensors.

Authors:  B M de Boer; J A H M Kahlman; T P G H Jansen; H Duric; J Veen
Journal:  Biosens Bioelectron       Date:  2006-11-02       Impact factor: 10.618

2.  Multiplex protein assays based on real-time magnetic nanotag sensing.

Authors:  Sebastian J Osterfeld; Heng Yu; Richard S Gaster; Stefano Caramuta; Liang Xu; Shu-Jen Han; Drew A Hall; Robert J Wilson; Shouheng Sun; Robert L White; Ronald W Davis; Nader Pourmand; Shan X Wang
Journal:  Proc Natl Acad Sci U S A       Date:  2008-12-12       Impact factor: 11.205

3.  Giant magnetoresistive biochip for DNA detection and HPV genotyping.

Authors:  Liang Xu; Heng Yu; Michael S Akhras; Shu-Jen Han; Sebastian Osterfeld; Robert L White; Nader Pourmand; Shan X Wang
Journal:  Biosens Bioelectron       Date:  2008-04-08       Impact factor: 10.618

4.  Spin valve sensors for ultrasensitive detection of superparamagnetic nanoparticles for biological applications.

Authors:  Guanxiong Li; Shouheng Sun; Robert J Wilson; Robert L White; Nader Pourmand; Shan X Wang
Journal:  Sens Actuators A Phys       Date:  2006       Impact factor: 3.407

5.  A biosensor based on magnetoresistance technology.

Authors:  D R Baselt; G U Lee; M Natesan; S W Metzger; P E Sheehan; R J Colton
Journal:  Biosens Bioelectron       Date:  1998-10-01       Impact factor: 10.618

6.  GMR biosensor arrays: correction techniques for reproducibility and enhanced sensitivity.

Authors:  D A Hall; R S Gaster; S J Osterfeld; B Murmann; S X Wang
Journal:  Biosens Bioelectron       Date:  2010-02-06       Impact factor: 10.618

7.  GMR biosensor arrays: a system perspective.

Authors:  D A Hall; R S Gaster; T Lin; S J Osterfeld; S Han; B Murmann; S X Wang
Journal:  Biosens Bioelectron       Date:  2010-02-06       Impact factor: 10.618

8.  Matrix-insensitive protein assays push the limits of biosensors in medicine.

Authors:  Richard S Gaster; Drew A Hall; Carsten H Nielsen; Sebastian J Osterfeld; Heng Yu; Kathleen E Mach; Robert J Wilson; Boris Murmann; Joseph C Liao; Sanjiv S Gambhir; Shan X Wang
Journal:  Nat Med       Date:  2009-10-11       Impact factor: 53.440

  8 in total
  3 in total

1.  From saliva to SNP: non-invasive, point-of-care genotyping for precision medicine applications using recombinase polymerase amplification and giant magnetoresistive nanosensors.

Authors:  Ana Sofia de Olazarra; Dana Lee Cortade; Shan X Wang
Journal:  Lab Chip       Date:  2022-05-31       Impact factor: 7.517

2.  Enzymatic synthesis of magnetic nanoparticles.

Authors:  Arati G Kolhatkar; Chamath Dannongoda; Katerina Kourentzi; Andrew C Jamison; Ivan Nekrashevich; Archana Kar; Eliedonna Cacao; Ulrich Strych; Irene Rusakova; Karen S Martirosyan; Dmitri Litvinov; T Randall Lee; Richard C Willson
Journal:  Int J Mol Sci       Date:  2015-04-03       Impact factor: 5.923

3.  Magnetic Sensing Potential of Fe3O4 Nanocubes Exceeds That of Fe3O4 Nanospheres.

Authors:  Arati G Kolhatkar; Yi-Ting Chen; Pawilai Chinwangso; Ivan Nekrashevich; Gamage C Dannangoda; Ankit Singh; Andrew C Jamison; Oussama Zenasni; Irene A Rusakova; Karen S Martirosyan; Dmitri Litvinov; Shoujun Xu; Richard C Willson; T Randall Lee
Journal:  ACS Omega       Date:  2017-11-16
  3 in total

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