Literature DB >> 22493972

Misconceptions about coercion and undue influence: reflections on the views of IRB members.

Emily Largent1, Christine Grady, Franklin G Miller, Alan Wertheimer.   

Abstract

Payment to recruit research subjects is a common practice but raises ethical concerns relating to the potential for coercion or undue influence. We conducted the first national study of IRB members and human subjects protection professionals to explore attitudes as to whether and why payment of research participants constitutes coercion or undue influence. Upon critical evaluation of the cogency of ethical concerns regarding payment, as reflected in our survey results, we found expansive or inconsistent views about coercion and undue influence that may interfere with valuable research. In particular, respondents appear to believe that coercion and undue influence lie on a continuum; by contrast, we argue that they are wholly distinct: whereas undue influence is a cognitive distortion relating to assessment of risks and benefits, coercion is a threat of harm. Because payment is an offer, rather than a threat, payment is never coercive.
© 2012 John Wiley & Sons Ltd.

Entities:  

Keywords:  coercion; payment; undue influence

Mesh:

Year:  2012        PMID: 22493972      PMCID: PMC4943210          DOI: 10.1111/j.1467-8519.2012.01972.x

Source DB:  PubMed          Journal:  Bioethics        ISSN: 0269-9702            Impact factor:   1.898


  11 in total

Review 1.  Money for research participation: does in jeopardize informed consent?

Authors:  C Grady
Journal:  Am J Bioeth       Date:  2001       Impact factor: 11.229

2.  Undue inducement: nonsense on stilts?

Authors:  Ezekiel J Emanuel
Journal:  Am J Bioeth       Date:  2005 Sep-Oct       Impact factor: 11.229

3.  Payment for research participation: a coercive offer?

Authors:  A Wertheimer; F G Miller
Journal:  J Med Ethics       Date:  2008-05       Impact factor: 2.903

Review 4.  Experimental philosophy and the problem of free will.

Authors:  Shaun Nichols
Journal:  Science       Date:  2011-03-18       Impact factor: 47.728

5.  False hopes and best data: consent to research and the therapeutic misconception.

Authors:  P S Appelbaum; L H Roth; C W Lidz; P Benson; W Winslade
Journal:  Hastings Cent Rep       Date:  1987-04       Impact factor: 2.683

6.  Why do we pay? A national survey of investigators and IRB chairpersons.

Authors:  Elizabeth Ripley; Francis Macrina; Monika Markowitz; Chris Gennings
Journal:  J Empir Res Hum Res Ethics       Date:  2010-09       Impact factor: 1.742

7.  Money, coercion, and undue inducement: attitudes about payments to research participants.

Authors:  Emily A Largent; Christine Grady; Franklin G Miller; Alan Wertheimer
Journal:  IRB       Date:  2012 Jan-Feb

Review 8.  More than the money: a review of the literature examining healthy volunteer motivations.

Authors:  Leanne Stunkel; Christine Grady
Journal:  Contemp Clin Trials       Date:  2010-12-10       Impact factor: 2.226

9.  Paying Clinical Research Participants: One Institution's Research Ethics Committees' Perspective.

Authors:  Elizabeth B D Ripley; Frank L Macrina; Monika Markowitz
Journal:  J Empir Res Hum Res Ethics       Date:  2006-12       Impact factor: 1.742

10.  Voluntariness of consent to research: a conceptual model.

Authors:  Paul S Appelbaum; Charles W Lidz; Robert Klitzman
Journal:  Hastings Cent Rep       Date:  2009 Jan-Feb       Impact factor: 2.683

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  14 in total

1.  Nudges and coercion: conceptual, empirical, and normative considerations.

Authors:  Kelso Cratsley
Journal:  Monash Bioeth Rev       Date:  2015 Jun-Sep

2.  Avoiding Exploitation in Phase I Clinical Trials: More than (Un)Just Compensation.

Authors:  Matt Lamkin; Carl Elliott
Journal:  J Law Med Ethics       Date:  2018-03-27       Impact factor: 1.718

3.  An Ethical Exploration of Barriers to Research on Controlled Drugs.

Authors:  Michael H Andreae; Evelyn Rhodes; Tyler Bourgoise; George M Carter; Robert S White; Debbie Indyk; Henry Sacks; Rosamond Rhodes
Journal:  Am J Bioeth       Date:  2016       Impact factor: 11.229

4.  A Qualitative Analysis of Ethical Perspectives on Recruitment and Consent for Human Intracranial Electrophysiology Studies.

Authors:  Joncarmen V Mergenthaler; Winston Chiong; Daniel Dohan; Josh Feler; Cailin R Lechner; Philip A Starr; Jalayne J Arias
Journal:  AJOB Neurosci       Date:  2021-01

5.  "Money Helps": People who inject drugs and their perceptions of financial compensation and its ethical implications.

Authors:  Roberto Abadie; Brandon Brown; Celia B Fisher
Journal:  Ethics Behav       Date:  2018-11-05

6.  Incentives to participate in clinical trials: practical and ethical considerations.

Authors:  Steven L Bernstein; James Feldman
Journal:  Am J Emerg Med       Date:  2015-05-29       Impact factor: 2.469

Review 7.  The potential exploitation of research participants in high income countries who lack access to health care.

Authors:  Rafael Dal-Ré; Annette Rid; Ezekiel Emanuel; David Wendler
Journal:  Br J Clin Pharmacol       Date:  2016-02-29       Impact factor: 4.335

8.  How IRBs view and make decisions about coercion and undue influence.

Authors:  Robert Klitzman
Journal:  J Med Ethics       Date:  2012-09-14       Impact factor: 2.903

9.  Bioethical Issues in Providing Financial Incentives to Research Participants.

Authors:  David B Resnik
Journal:  Medicoleg Bioeth       Date:  2015-06-24

10.  Financial Incentives to Motivate Pediatric HIV Testing-Assessing the Potential for Coercion, Inducement, and Voluntariness.

Authors:  Anjuli D Wagner; Seema K Shah; Irene N Njuguna; Kathryn M Porter; Jillian Neary; Elizabeth Maleche-Obimbo; Rose Bosire; Dalton C Wamalwa; Grace C John-Stewart; Jennifer A Slyker
Journal:  J Acquir Immune Defic Syndr       Date:  2018-07-01       Impact factor: 3.731

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