| Literature DB >> 22493796 |
Khoon S Lim1, Joydip Kundu, April Reeves, Laura A Poole-Warren, Subhas C Kundu, Penny J Martens.
Abstract
Sericin peptides and PVA are chemically modified with methacrylate groups to produce a covalent PVA/sericin hydrogel. Preservation of the sericin bioactivity following methacrylation is confirmed, and PVA/sericin hydrogels are fabricated for both B. mori and A. mylitta sericin. Cell adhesion studies confirm the preservation of sericin bioactivity post incorporation in PVA gels. PVA/A. mylitta gels are observed to facilitate cell adhesion to a significantly greater degree than PVA/B. mori gels. Overall, the incorporation of sericin does not alter the physical properties of the PVA hydrogels but does result in significantly improved cellular interaction, particularly from A. mylitta gels.Entities:
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Year: 2012 PMID: 22493796 DOI: 10.1002/mabi.201100292
Source DB: PubMed Journal: Macromol Biosci ISSN: 1616-5187 Impact factor: 4.979