Literature DB >> 22492495

Synthesis and immunostimulating properties of novel adamant-1-yl tripeptides.

Rosana Ribić1, Lidija Habjanec, Branka Vranešić, Ruža Frkanec, Srđanka Tomić.   

Abstract

The aim of this work was to prepare L- and D-(adamant-1-yl)-Gly-L-Ala-D-isoGln peptides in order to study their adjuvant (immunostimulating) activities. Adjuvant activity of adamant-1-yl tripeptides was tested in the mouse model using ovalbumin as an antigen and in comparison to the peptidoglycan monomer (PGM; β-D-GlcNAc-(1→4)-D-MurNAc-L-Ala-D-isoGln-mesoDAP(εNH(2) )-D-Ala-D-Ala) and structurally related adamant-2-yl tripeptides.
Copyright © 2012 Verlag Helvetica Chimica Acta AG, Zürich.

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Year:  2012        PMID: 22492495     DOI: 10.1002/cbdv.201100232

Source DB:  PubMed          Journal:  Chem Biodivers        ISSN: 1612-1872            Impact factor:   2.408


  5 in total

1.  In vitro antiproliferative study of novel adamantyl pyridin-4-ones.

Authors:  V Petrović Peroković; Ž Car; T Opačak-Bernardi; I Martin-Kleiner; M Kralj; S Tomić
Journal:  Mol Divers       Date:  2017-07-10       Impact factor: 2.943

Review 2.  Adamantane in Drug Delivery Systems and Surface Recognition.

Authors:  Adela Štimac; Marina Šekutor; Kata Mlinarić-Majerski; Leo Frkanec; Ruža Frkanec
Journal:  Molecules       Date:  2017-02-16       Impact factor: 4.411

3.  Adamantane Containing Peptidoglycan Fragments Enhance RANTES and IL-6 Production in Lipopolysaccharide-Induced Macrophages.

Authors:  Mateja Manček-Keber; Rosana Ribić; Fernando Chain; Davy Sinnaeve; José C Martins; Roman Jerala; Srđanka Tomić; Krisztina Fehér
Journal:  Molecules       Date:  2020-08-14       Impact factor: 4.411

4.  Design, Synthesis, and Biological Evaluation of Desmuramyl Dipeptides Modified by Adamantyl-1,2,3-triazole.

Authors:  Vesna Petrović Peroković; Željka Car; Josip Draženović; Ranko Stojković; Lidija Milković; Mariastefania Antica; Đani Škalamera; Srđanka Tomić; Rosana Ribić
Journal:  Molecules       Date:  2021-10-21       Impact factor: 4.411

5.  Synthesis and Immunological Evaluation of Mannosylated Desmuramyl Dipeptides Modified by Lipophilic Triazole Substituents.

Authors:  Vesna Petrović Peroković; Željka Car; Mia Bušljeta; Danijela Mihelec; Marija Paurević; Siniša Ivanković; Ranko Stojković; Rosana Ribić
Journal:  Int J Mol Sci       Date:  2022-08-03       Impact factor: 6.208

  5 in total

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