Literature DB >> 2249248

Role of the CDC8 gene in the repair of single strand breaks in DNA of the yeast Saccharomyces cerevisiae.

H Baranowska1, D Zaborowska, W J Jachymczyk, J Zuk.   

Abstract

It has been found that the repair of single strand breaks is defective in the DNA replication mutants cdc8-1 and cdc8-3 of Saccharomyces cerevisiae both in permissive (23 degrees C) and restrictive conditions (36 degrees C). In permissive conditions we observed a significant delay in single strand break repair in a diploid strain HB7 (cdc8-1/cdc8-1), as compared with the wild-type strain. Under restrictive conditions no repair was observed, but rather degradation of MMS-damaged DNA occurred. It has been also found that the repair of single strand breaks in yeast is inhibited by cycloheximide but not by hydroxyurea.

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Year:  1990        PMID： 2249248     DOI： 10.1007/bf00318376

Source DB:  PubMed          Journal:  Curr Genet        ISSN： 0172-8083            Impact factor:   3.886


  16 in total

Review 1.  Saccharomyces cerevisiae cell cycle.

Authors:  L H Hartwell
Journal:  Bacteriol Rev       Date:  1974-06

2.  Replication of the nuclear genome in yeast does not require concomitant protein synthesis.

Authors:  D H Williamson
Journal:  Biochem Biophys Res Commun       Date:  1973-06-08       Impact factor: 3.575

3.  Three additional genes required for deoxyribonucleic acid synthesis in Saccharomyces cerevisiae.

Authors:  L H Hartwell
Journal:  J Bacteriol       Date:  1973-09       Impact factor: 3.490

4.  Genetic control of the cell division cycle in yeast. II. Genes controlling DNA replication and its initiation.

Authors:  L H Hartwell
Journal:  J Mol Biol       Date:  1971-07-14       Impact factor: 5.469

5.  Induction of polypeptides in Saccharomyces cerevisiae after ultraviolet irradiation.

Authors:  J F Angulo; J Schwencke; I Fernandez; E Moustacchi
Journal:  Biochem Biophys Res Commun       Date:  1986-07-31       Impact factor: 3.575

6.  Sequential function of gene products relative to DNA synthesis in the yeast cell cycle.

Authors:  L H Hartwell
Journal:  J Mol Biol       Date:  1976-07-15       Impact factor: 5.469

7.  Saccharomyces cerevisiae CDC8 gene and its product.

Authors:  L G Birkenmeyer; J C Hill; L B Dumas
Journal:  Mol Cell Biol       Date:  1984-04       Impact factor: 4.272

8.  Yeast gene CDC8 encodes thymidylate kinase and is complemented by herpes thymidine kinase gene TK.

Authors:  R A Sclafani; W L Fangman
Journal:  Proc Natl Acad Sci U S A       Date:  1984-09       Impact factor: 11.205

9.  Effect of reversible inhibition of deoxyribonucleic acid synthesis on the yeast cell cycle.

Authors:  M L Slater
Journal:  J Bacteriol       Date:  1973-01       Impact factor: 3.490

10.  Decreased UV mutagenesis in cdc8, a DNA replication mutant of Saccharomyces cerevisiae.

Authors:  L Prakash; D Hinkle; S Prakash
Journal:  Mol Gen Genet       Date:  1979
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  2 in total

1.  Cloning, expression in Escherichia coli, and characterization of Arabidopsis thaliana UMP/CMP kinase.

Authors:  L Zhou; F Lacroute; R Thornburg
Journal:  Plant Physiol       Date:  1998-05       Impact factor: 8.340

2.  DNA polymerase III is required for DNA repair in Saccharomyces cerevisiae.

Authors:  W Suszek; H Baranowska; J Zuk; W J Jachymczyk
Journal:  Curr Genet       Date:  1993-09       Impact factor: 3.886
  2 in total

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