BACKGROUND: Evidence of the effectiveness of lipid-based ready-to-use complementary foods (RUCF) at improving linear growth among infants aged 6-12 mo is scarce, and further work is warranted. OBJECTIVE: The objective was to assess the effectiveness of a fortified soybean-maize-sorghum RUCF paste compared with a fortified corn soy blend (UNIMIX) porridge on the prevalence of underweight and stunting among infants in South Kivu Province, Democratic Republic of Congo. DESIGN: Infants were randomly assigned at 6 mo of age to receive either RUCF (n = 691) or UNIMIX (n = 692) for 6 mo. In addition to admission and monthly anthropometric measurements, hemoglobin, triglyceride, and cholesterol were measured at enrollment and at the end of the study. RESULTS: No significant differences in the prevalence of stunting (RUCF: 48.6%; UNIMIX: 46.4%; P = 0.31), the prevalence of underweight (RUCF: 20.4%; UNIMIX: 18.2%; P = 0.42), or weight gain (RUCF: 1.2 ± 0.7 kg; UNIMIX: 1.3 ± 0.7 kg; P = 0.08) were found. A small but statistically significant difference in length gain (RUCF: 5.2 ± 2.0; UNIMIX: 5.4 ± 2.0; P = 0.03) was found. No significant differences in the concentrations of hemoglobin, serum triglyceride, and serum cholesterol were found between the 2 groups. CONCLUSION: No significant differences were found between the RUCF and UNIMIX in the reduction of the prevalence of stunting and underweight at 12 mo of age among rural Congolese infants. This trial was registered at controlled-trials.com as ISRCTN20267635.
RCT Entities:
BACKGROUND: Evidence of the effectiveness of lipid-based ready-to-use complementary foods (RUCF) at improving linear growth among infants aged 6-12 mo is scarce, and further work is warranted. OBJECTIVE: The objective was to assess the effectiveness of a fortified soybean-maize-sorghumRUCF paste compared with a fortified corn soy blend (UNIMIX) porridge on the prevalence of underweight and stunting among infants in South Kivu Province, Democratic Republic of Congo. DESIGN:Infants were randomly assigned at 6 mo of age to receive either RUCF (n = 691) or UNIMIX (n = 692) for 6 mo. In addition to admission and monthly anthropometric measurements, hemoglobin, triglyceride, and cholesterol were measured at enrollment and at the end of the study. RESULTS: No significant differences in the prevalence of stunting (RUCF: 48.6%; UNIMIX: 46.4%; P = 0.31), the prevalence of underweight (RUCF: 20.4%; UNIMIX: 18.2%; P = 0.42), or weight gain (RUCF: 1.2 ± 0.7 kg; UNIMIX: 1.3 ± 0.7 kg; P = 0.08) were found. A small but statistically significant difference in length gain (RUCF: 5.2 ± 2.0; UNIMIX: 5.4 ± 2.0; P = 0.03) was found. No significant differences in the concentrations of hemoglobin, serum triglyceride, and serum cholesterol were found between the 2 groups. CONCLUSION: No significant differences were found between the RUCF and UNIMIX in the reduction of the prevalence of stunting and underweight at 12 mo of age among rural Congolese infants. This trial was registered at controlled-trials.com as ISRCTN20267635.
Authors: Jai K Das; Rehana A Salam; Yousaf Bashir Hadi; Sana Sadiq Sheikh; Afsah Z Bhutta; Zita Weise Prinzo; Zulfiqar A Bhutta Journal: Cochrane Database Syst Rev Date: 2019-05-02
Authors: Ilana R Cliffer; Laetitia Nikiema; Breanne K Langlois; Augustin N Zeba; Ye Shen; Hermann B Lanou; Devika J Suri; Franck Garanet; Kenneth Chui; Stephen Vosti; Shelley Walton; Irwin Rosenberg; Patrick Webb; Beatrice L Rogers Journal: Curr Dev Nutr Date: 2020-01-23
Authors: Maria N Garcia-Casal; Juan Pablo Peña-Rosas; Luz Maria De-Regil; Jeffrey A Gwirtz; Sant-Rayn Pasricha Journal: Cochrane Database Syst Rev Date: 2018-12-22
Authors: Sonja Y Hess; Souheila Abbeddou; Elizabeth Yakes Jimenez; Jérôme W Somé; Stephen A Vosti; Zinéwendé P Ouédraogo; Rosemonde M Guissou; Jean-Bosco Ouédraogo; Kenneth H Brown Journal: PLoS One Date: 2015-03-27 Impact factor: 3.240
Authors: Tahmeed Ahmed; Nuzhat Choudhury; M Iqbal Hossain; Nattapol Tangsuphoom; M Munirul Islam; Saskia de Pee; Georg Steiger; Rachel Fuli; Shafiqul A M Sarker; Monira Parveen; Keith P West; Parul Christian Journal: BMC Pediatr Date: 2014-06-27 Impact factor: 2.125