BACKGROUND: Middle-aged and older adults with diabetes are heterogeneous and may be characterized as belonging to one of three clinical groups: a relatively healthy group, a group having characteristics likely to make diabetes self-management difficult, and a group with poor health status for whom current management targets have uncertain benefit. METHODS: We analyzed waves 2004-2008 of the Health and Retirement Study and the supplemental Health and Retirement Study 2003 Diabetes Study. The sample included adults with diabetes 51 years and older (n = 3,507, representing 13.6 million in 2004). We investigated the mortality outcomes for the three clinical groups, using survival analysis and Cox proportional hazard models. RESULTS: The 5-year survival probabilities were Relatively Healthy Group, 90.8%; Self-Management Difficulty Group, 79.4%; and Uncertain Benefit Group, 52.5%. For all age groups and clinical groups, except those 76 years and older in the Uncertain Benefit Group, survival exceeded 50%. CONCLUSIONS: This study reveals the substantial survival of middle-aged and older adults with diabetes, regardless of health status. These findings have implications for the clinical management of and future research about diabetes patients with multiple comorbidities.
BACKGROUND: Middle-aged and older adults with diabetes are heterogeneous and may be characterized as belonging to one of three clinical groups: a relatively healthy group, a group having characteristics likely to make diabetes self-management difficult, and a group with poor health status for whom current management targets have uncertain benefit. METHODS: We analyzed waves 2004-2008 of the Health and Retirement Study and the supplemental Health and Retirement Study 2003 Diabetes Study. The sample included adults with diabetes 51 years and older (n = 3,507, representing 13.6 million in 2004). We investigated the mortality outcomes for the three clinical groups, using survival analysis and Cox proportional hazard models. RESULTS: The 5-year survival probabilities were Relatively Healthy Group, 90.8%; Self-Management Difficulty Group, 79.4%; and Uncertain Benefit Group, 52.5%. For all age groups and clinical groups, except those 76 years and older in the Uncertain Benefit Group, survival exceeded 50%. CONCLUSIONS: This study reveals the substantial survival of middle-aged and older adults with diabetes, regardless of health status. These findings have implications for the clinical management of and future research about diabetespatients with multiple comorbidities.
Authors: Christine T Cigolle; Kenneth M Langa; Mohammed U Kabeto; Zhiyi Tian; Caroline S Blaum Journal: Ann Intern Med Date: 2007-08-07 Impact factor: 25.391
Authors: Karen N Barnett; Marion E T McMurdo; Simon A Ogston; Andrew D Morris; Josie M M Evans Journal: Age Ageing Date: 2006-05-05 Impact factor: 10.668
Authors: Laura N McEwen; Catherine Kim; Andrew J Karter; Mary N Haan; Debashis Ghosh; Paula M Lantz; Carol M Mangione; Theodore J Thompson; William H Herman Journal: Diabetes Care Date: 2007-04-27 Impact factor: 19.112
Authors: Kasia J Lipska; Joseph S Ross; Yinghui Miao; Nilay D Shah; Sei J Lee; Michael A Steinman Journal: JAMA Intern Med Date: 2015-03 Impact factor: 21.873
Authors: Derek LeRoith; Geert Jan Biessels; Susan S Braithwaite; Felipe F Casanueva; Boris Draznin; Jeffrey B Halter; Irl B Hirsch; Marie E McDonnell; Mark E Molitch; M Hassan Murad; Alan J Sinclair Journal: J Clin Endocrinol Metab Date: 2019-05-01 Impact factor: 5.958
Authors: Christine T Cigolle; Corey L Nagel; Caroline S Blaum; Jersey Liang; Ana R Quiñones Journal: J Gerontol B Psychol Sci Soc Sci Date: 2018-06-14 Impact factor: 4.077
Authors: Medha N Munshi; Graydon S Meneilly; Leocadio Rodríguez-Mañas; Kelly L Close; Paul R Conlin; Tali Cukierman-Yaffe; Angus Forbes; Om P Ganda; C Ronald Kahn; Elbert Huang; Lori M Laffel; Christine G Lee; Sei Lee; David M Nathan; Naushira Pandya; Richard Pratley; Robert Gabbay; Alan J Sinclair Journal: Lancet Diabetes Endocrinol Date: 2020-10 Impact factor: 32.069
Authors: Vania Leung; Kristen Wroblewski; L Philip Schumm; Megan Huisingh-Scheetz; Elbert S Huang Journal: J Gerontol A Biol Sci Med Sci Date: 2021-10-13 Impact factor: 6.053