Literature DB >> 22491969

You want to do what? My mother's choice to have direct-to-consumer genetic testing.

Elizabeth A Varga1.   

Abstract

As a genetic counselor, I had mixed opinions when my mother told me of her intent to undergo genomewide, SNP-based direct-to-consumer (DTC) genetic testing. I cautioned her that results could be misleading, could increase anxiety and were often of limited clinical validity or utility. I warned of the possibility of learning unintended health information and expressed concerns about how the information might be used by a private company. I told her about the variability in results among companies. Yet, she persisted in her desire, reminding me that she was an informed consumer. After reviewing her goals and understanding of the information she might receive, she elected to proceed. Despite my insistence that I would not be her personal genetic counselor, when the results came back, I found myself immersed in her genetic data. In this manuscript, I will examine how this personal experience challenged my perceptions of DTC testing.

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Year:  2012        PMID: 22491969     DOI: 10.1007/s10897-012-9482-1

Source DB:  PubMed          Journal:  J Genet Couns        ISSN: 1059-7700            Impact factor:   2.537


  4 in total

1.  Inconsistent results, inaccurate claims plague direct-to-consumer gene tests.

Authors:  Bridget M Kuehn
Journal:  JAMA       Date:  2010-09-22       Impact factor: 56.272

2.  Effect of direct-to-consumer genomewide profiling to assess disease risk.

Authors:  Cinnamon S Bloss; Nicholas J Schork; Eric J Topol
Journal:  N Engl J Med       Date:  2011-01-12       Impact factor: 91.245

Review 3.  Predictive genetic testing: psychological factors.

Authors:  P M Salkovskis; K A Rimes
Journal:  J Psychosom Res       Date:  1997-11       Impact factor: 3.006

Review 4.  Use of genomic profiling to assess risk for cardiovascular disease and identify individualized prevention strategies--a targeted evidence-based review.

Authors:  Glenn E Palomaki; Stephanie Melillo; Louis Neveux; Michael P Douglas; W David Dotson; A Cecile J W Janssens; Elizabeth A Balkite; Linda A Bradley
Journal:  Genet Med       Date:  2010-12       Impact factor: 8.822

  4 in total

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