Literature DB >> 22491948

ADITEC: joining forces for next-generation vaccines.

Rino Rappuoli1, Donata Medaglini.   

Abstract

Scientists sit poised at a singular moment in the history of vaccine research. Genomics and systems biology have fueled advances in our understanding of human immunology. Together with adjuvant development and structure-based design of immunogens, these next-generation technologies are transforming the field of vaccinology and shaping the future of medicine. However, the sophisticated science behind the development of modern vaccines and the resulting knotty ethical issues have become so complex that scientists and policy-makers need a new model for vaccine research. The European Commission-sponsored Advanced Immunization Technologies project--ADITEC--brings together some of the leading laboratories in the field to tackle the problems that no lab can tackle in isolation.

Entities:  

Mesh:

Substances:

Year:  2012        PMID: 22491948     DOI: 10.1126/scitranslmed.3003826

Source DB:  PubMed          Journal:  Sci Transl Med        ISSN: 1946-6234            Impact factor:   17.956


  9 in total

Review 1.  Ebola vaccine R&D: Filling the knowledge gaps.

Authors:  Donata Medaglini; Ali M Harandi; Tom H M Ottenhoff; Claire-Anne Siegrist
Journal:  Sci Transl Med       Date:  2015-12-09       Impact factor: 17.956

2.  Modulation of Primary Immune Response by Different Vaccine Adjuvants.

Authors:  Annalisa Ciabattini; Elena Pettini; Fabio Fiorino; Gabiria Pastore; Peter Andersen; Gianni Pozzi; Donata Medaglini
Journal:  Front Immunol       Date:  2016-10-17       Impact factor: 7.561

3.  Transcriptomics of the Vaccine Immune Response: Priming With Adjuvant Modulates Recall Innate Responses After Boosting.

Authors:  Francesco Santoro; Elena Pettini; Dmitri Kazmin; Annalisa Ciabattini; Fabio Fiorino; Gregor D Gilfillan; Ida M Evenroed; Peter Andersen; Gianni Pozzi; Donata Medaglini
Journal:  Front Immunol       Date:  2018-06-05       Impact factor: 7.561

4.  Editorial: Advanced Immunization Technologies for Next Generation Vaccines.

Authors:  Donata Medaglini; Peter Andersen; Rino Rappuoli
Journal:  Front Immunol       Date:  2020-05-06       Impact factor: 7.561

5.  Long-Term Anti-Bacterial Immunity against Systemic Infection by Salmonella enterica Serovar Typhimurium Elicited by a GMMA-Based Vaccine.

Authors:  Fabio Fiorino; Elena Pettini; Oliver Koeberling; Annalisa Ciabattini; Gianni Pozzi; Laura B Martin; Donata Medaglini
Journal:  Vaccines (Basel)       Date:  2021-05-12

Review 6.  Application of "Systems Vaccinology" to Evaluate Inflammation and Reactogenicity of Adjuvanted Preventative Vaccines.

Authors:  David J M Lewis; Mark P Lythgoe
Journal:  J Immunol Res       Date:  2015-08-25       Impact factor: 4.818

7.  Prediction of individual immune responsiveness to a candidate vaccine by a systems vaccinology approach.

Authors:  Annacarmen Petrizzo; Maria Tagliamonte; Maria Lina Tornesello; Franco M Buonaguro; Luigi Buonaguro
Journal:  J Transl Med       Date:  2014-01-15       Impact factor: 5.531

8.  Overcoming the Neonatal Limitations of Inducing Germinal Centers through Liposome-Based Adjuvants Including C-Type Lectin Agonists Trehalose Dibehenate or Curdlan.

Authors:  Maria Vono; Christiane Sigrid Eberhardt; Elodie Mohr; Floriane Auderset; Dennis Christensen; Mirco Schmolke; Rhea Coler; Andreas Meinke; Peter Andersen; Paul-Henri Lambert; Beatris Mastelic-Gavillet; Claire-Anne Siegrist
Journal:  Front Immunol       Date:  2018-02-28       Impact factor: 7.561

9.  Systematic Evaluation of Kinetics and Distribution of Muscle and Lymph Node Activation Measured by 18F-FDG- and 11C-PBR28-PET/CT Imaging, and Whole Blood and Muscle Transcriptomics After Immunization of Healthy Humans With Adjuvanted and Unadjuvanted Vaccines.

Authors:  Zarni Win; January Weiner Rd; Allan Listanco; Neva Patel; Rohini Sharma; Aldona Greenwood; Jeroen Maertzdorf; Hans-Joachim Mollenkopf; Kat Pizzoferro; Thomas Cole; Caroline L Bodinham; Stefan H E Kaufmann; Philippe Denoel; Giuseppe Del Giudice; David J M Lewis
Journal:  Front Immunol       Date:  2021-02-05       Impact factor: 7.561

  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.