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Literature DB >> 22491478

Time is of the essence: microRNAs and age-associated neurodegeneration.

Abstract

Aging is a key risk factor in neurodegenerative disease; however, little is known about cellular pathways that mediate age-associated degeneration of the brain. The Bonini lab has identified a conserved microRNA, miR-34, that plays a neuroprotective role in the aging Drosophila brain and suggests that it functions in temporal control of gene expression.

Entities: Chemical Disease Gene Species

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Year: 2012 PMID： 22491478 PMCID： PMC3411169 DOI： 10.1038/cr.2012.59

Source DB: PubMed Journal: Cell Res ISSN： 1001-0602 Impact factor: 25.617

15 in total

Review 1. The genetics of ageing.

Authors: Cynthia J Kenyon
Journal: Nature Date: 2010-03-25 Impact factor: 49.962

2. Animal MicroRNAs confer robustness to gene expression and have a significant impact on 3'UTR evolution.

Authors: Alexander Stark; Julius Brennecke; Natascha Bushati; Robert B Russell; Stephen M Cohen
Journal: Cell Date: 2005-12-16 Impact factor: 41.582

3. MicroRNA pathways modulate polyglutamine-induced neurodegeneration.

Authors: Julide Bilen; Nan Liu; Barrington G Burnett; Randall N Pittman; Nancy M Bonini
Journal: Mol Cell Date: 2006-10-06 Impact factor: 17.970

4. Regulation of synaptic structure and function by FMRP-associated microRNAs miR-125b and miR-132.

Authors: Dieter Edbauer; Joel R Neilson; Kelly A Foster; Chi-Fong Wang; Daniel P Seeburg; Matthew N Batterton; Tomoko Tada; Bridget M Dolan; Phillip A Sharp; Morgan Sheng
Journal: Neuron Date: 2010-02-11 Impact factor: 17.173

Review 5. Pathogenic protein seeding in Alzheimer disease and other neurodegenerative disorders.

Authors: Mathias Jucker; Lary C Walker
Journal: Ann Neurol Date: 2011-10 Impact factor: 10.422

6. A MicroRNA feedback circuit in midbrain dopamine neurons.

Authors: Jongpil Kim; Keiichi Inoue; Jennifer Ishii; William B Vanti; Sergey V Voronov; Elizabeth Murchison; Gregory Hannon; Asa Abeliovich
Journal: Science Date: 2007-08-31 Impact factor: 47.728

7. The conserved microRNA miR-8 tunes atrophin levels to prevent neurodegeneration in Drosophila.

Authors: Janina S Karres; Valérie Hilgers; Ines Carrera; Jessica Treisman; Stephen M Cohen
Journal: Cell Date: 2007-10-05 Impact factor: 41.582

8. The microRNA miR-34 modulates ageing and neurodegeneration in Drosophila.

Authors: Nan Liu; Michael Landreh; Kajia Cao; Masashi Abe; Gert-Jan Hendriks; Jason R Kennerdell; Yongqing Zhu; Li-San Wang; Nancy M Bonini
Journal: Nature Date: 2012-02-15 Impact factor: 49.962

9. A novel pathway regulates memory and plasticity via SIRT1 and miR-134.

Authors: Jun Gao; Wen-Yuan Wang; Ying-Wei Mao; Johannes Gräff; Ji-Song Guan; Ling Pan; Gloria Mak; Dohoon Kim; Susan C Su; Li-Huei Tsai
Journal: Nature Date: 2010-07-11 Impact factor: 49.962

Review 10. Genomics of human longevity.

Authors: P E Slagboom; M Beekman; W M Passtoors; J Deelen; A A M Vaarhorst; J M Boer; E B van den Akker; D van Heemst; A J M de Craen; A B Maier; M Rozing; S P Mooijaart; B T Heijmans; R G J Westendorp
Journal: Philos Trans R Soc Lond B Biol Sci Date: 2011-01-12 Impact factor: 6.237

7 in total

1. miR-25 alleviates polyQ-mediated cytotoxicity by silencing ATXN3.

Authors: Fengzhen Huang; Li Zhang; Zhe Long; Zhao Chen; Xuan Hou; Chunrong Wang; Huirong Peng; Junling Wang; Jiada Li; Ranhui Duan; Kun Xia; De-Maw Chuang; Beisha Tang; Hong Jiang
Journal: FEBS Lett Date: 2014-11-20 Impact factor: 4.124

2. Investigation of Gene Regulatory Networks Associated with Autism Spectrum Disorder Based on MiRNA Expression in China.

Authors: Fengzhen Huang; Zhe Long; Zhao Chen; Jiada Li; Zhengmao Hu; Rong Qiu; Wei Zhuang; Beisha Tang; Kun Xia; Hong Jiang
Journal: PLoS One Date: 2015-06-10 Impact factor: 3.240

3. Circulating MicroRNAs as easy-to-measure aging biomarkers in older breast cancer patients: correlation with chronological age but not with fitness/frailty status.

Authors: Sigrid Hatse; Barbara Brouwers; Bruna Dalmasso; Annouschka Laenen; Cindy Kenis; Patrick Schöffski; Hans Wildiers
Journal: PLoS One Date: 2014-10-21 Impact factor: 3.240

4. Deep sequencing identifies circulating mouse miRNAs that are functionally implicated in manifestations of aging and responsive to calorie restriction.

Authors: Joseph M Dhahbi; Stephen R Spindler; Hani Atamna; Amy Yamakawa; Noel Guerrero; Dario Boffelli; Patricia Mote; David I K Martin
Journal: Aging (Albany NY) Date: 2013-02 Impact factor: 5.682

5. Genome-wide assessment of post-transcriptional control in the fly brain.

Authors: Shaul Mezan; Reut Ashwal-Fluss; Rom Shenhav; Manuel Garber; Sebastian Kadener
Journal: Front Mol Neurosci Date: 2013-12-09 Impact factor: 5.639

Review 6. MicroRNAs and Presbycusis.

Authors: Weiming Hu; Junwu Wu; Wenjing Jiang; Jianguo Tang
Journal: Aging Dis Date: 2018-02-01 Impact factor: 6.745

7. Toward Understanding Non-coding RNA Roles in Intracranial Aneurysms and Subarachnoid Hemorrhage.

Authors: Fengzhen Huang; Jiping Yi; Tieqiao Zhou; Xiaoxiang Gong; Hong Jiang; Xiaoxi Yao
Journal: Transl Neurosci Date: 2017-05-31 Impact factor: 1.757

7 in total