Literature DB >> 22491356

A new player in the puzzle of filovirus entry.

Judith M White1, Kathryn L Schornberg.   

Abstract

Viruses of the genera Ebolavirus and Marburgvirus are filoviruses that cause haemorrhagic fever in primates, with extremely high fatality rates. Studies have focused on elucidating how these viruses enter host cells, with the aim of developing therapeutics. The ebolavirus glycoprotein has been found to play key parts in all steps of entry. Furthermore, recent studies have identified Niemann-Pick C1 (NPC1), a protein that resides deep in the endocytic pathway, as an important host factor in this process.

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Year:  2012        PMID： 22491356      PMCID： PMC3540776          DOI： 10.1038/nrmicro2764

Source DB:  PubMed          Journal:  Nat Rev Microbiol        ISSN： 1740-1526            Impact factor:   60.633


  59 in total

Review 1.  Late-penetrating viruses.

Authors:  Pierre-Yves Lozach; Jatta Huotari; Ari Helenius
Journal:  Curr Opin Virol       Date:  2011-06-12       Impact factor: 7.090

2.  Cell adhesion-dependent membrane trafficking of a binding partner for the ebolavirus glycoprotein is a determinant of viral entry.

Authors:  Derek Dube; Kathryn L Schornberg; Charles J Shoemaker; Sue E Delos; Tzanko S Stantchev; Kathleen A Clouse; Christopher C Broder; Judith M White
Journal:  Proc Natl Acad Sci U S A       Date:  2010-09-03       Impact factor: 11.205

3.  Niemann-Pick type C 1 function requires lumenal domain residues that mediate cholesterol-dependent NPC2 binding.

Authors:  Maika S Deffieu; Suzanne R Pfeffer
Journal:  Proc Natl Acad Sci U S A       Date:  2011-11-07       Impact factor: 11.205

4.  Conserved receptor-binding domains of Lake Victoria marburgvirus and Zaire ebolavirus bind a common receptor.

Authors:  Jens H Kuhn; Sheli R Radoshitzky; Alexander C Guth; Kelly L Warfield; Wenhui Li; Martin J Vincent; Jonathan S Towner; Stuart T Nichol; Sina Bavari; Hyeryun Choe; M Javad Aman; Michael Farzan
Journal:  J Biol Chem       Date:  2006-04-04       Impact factor: 5.157

5.  A forward genetic strategy reveals destabilizing mutations in the Ebolavirus glycoprotein that alter its protease dependence during cell entry.

Authors:  Anthony C Wong; Rohini G Sandesara; Nirupama Mulherkar; Sean P Whelan; Kartik Chandran
Journal:  J Virol       Date:  2010-01       Impact factor: 5.103

6.  Cathepsin cleavage potentiates the Ebola virus glycoprotein to undergo a subsequent fusion-relevant conformational change.

Authors:  Matthew Brecher; Kathryn L Schornberg; Sue E Delos; Marnie L Fusco; Erica Ollmann Saphire; Judith M White
Journal:  J Virol       Date:  2011-10-26       Impact factor: 5.103

7.  Endosomal proteolysis of the Ebola virus glycoprotein is necessary for infection.

Authors:  Kartik Chandran; Nancy J Sullivan; Ute Felbor; Sean P Whelan; James M Cunningham
Journal:  Science       Date:  2005-04-14       Impact factor: 47.728

8.  T-cell immunoglobulin and mucin domain 1 (TIM-1) is a receptor for Zaire Ebolavirus and Lake Victoria Marburgvirus.

Authors:  Andrew S Kondratowicz; Nicholas J Lennemann; Patrick L Sinn; Robert A Davey; Catherine L Hunt; Sven Moller-Tank; David K Meyerholz; Paul Rennert; Robert F Mullins; Melinda Brindley; Lindsay M Sandersfeld; Kathrina Quinn; Melodie Weller; Paul B McCray; John Chiorini; Wendy Maury
Journal:  Proc Natl Acad Sci U S A       Date:  2011-05-02       Impact factor: 11.205

Review 9.  Targeting cell entry of enveloped viruses as an antiviral strategy.

Authors:  Elodie Teissier; François Penin; Eve-Isabelle Pécheur
Journal:  Molecules       Date:  2010-12-30       Impact factor: 4.411

Review 10.  Correlates of protective immunity for Ebola vaccines: implications for regulatory approval by the animal rule.

Authors:  Nancy J Sullivan; Julie E Martin; Barney S Graham; Gary J Nabel
Journal:  Nat Rev Microbiol       Date:  2009-05       Impact factor: 60.633
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  45 in total

1.  Less is more: Ebola virus surface glycoprotein expression levels regulate virus production and infectivity.

Authors:  Gopi S Mohan; Ling Ye; Wenfang Li; Ana Monteiro; Xiaoqian Lin; Bishu Sapkota; Brian P Pollack; Richard W Compans; Chinglai Yang
Journal:  J Virol       Date:  2014-11-12       Impact factor: 5.103

2.  Ebolavirus Glycoprotein Directs Fusion through NPC1+ Endolysosomes.

Authors:  James A Simmons; Ryan S D'Souza; Margarida Ruas; Antony Galione; James E Casanova; Judith M White
Journal:  J Virol       Date:  2015-10-14       Impact factor: 5.103

3.  Ebolavirus entry requires a compact hydrophobic fist at the tip of the fusion loop.

Authors:  Sonia M Gregory; Per Larsson; Elizabeth A Nelson; Peter M Kasson; Judith M White; Lukas K Tamm
Journal:  J Virol       Date:  2014-04-02       Impact factor: 5.103

4.  Design and characterization of ebolavirus GP prehairpin intermediate mimics as drug targets.

Authors:  Tracy R Clinton; Matthew T Weinstock; Michael T Jacobsen; Nicolas Szabo-Fresnais; Maya J Pandya; Frank G Whitby; Andrew S Herbert; Laura I Prugar; Rena McKinnon; Christopher P Hill; Brett D Welch; John M Dye; Debra M Eckert; Michael S Kay
Journal:  Protein Sci       Date:  2014-10-31       Impact factor: 6.725

5.  Disentangling Viral Membrane Fusion from Receptor Binding Using Synthetic DNA-Lipid Conjugates.

Authors:  Robert J Rawle; Steven G Boxer; Peter M Kasson
Journal:  Biophys J       Date:  2016-07-12       Impact factor: 4.033

6.  Cell-cell contact promotes Ebola virus GP-mediated infection.

Authors:  Chunhui Miao; Minghua Li; Yi-Min Zheng; Fredric S Cohen; Shan-Lu Liu
Journal:  Virology       Date:  2015-12-03       Impact factor: 3.616

7.  Mapping of Ebolavirus Neutralization by Monoclonal Antibodies in the ZMapp Cocktail Using Cryo-Electron Tomography and Studies of Cellular Entry.

Authors:  Erin E H Tran; Elizabeth A Nelson; Pranay Bonagiri; James A Simmons; Charles J Shoemaker; Connie S Schmaljohn; Gary P Kobinger; Larry Zeitlin; Sriram Subramaniam; Judith M White
Journal:  J Virol       Date:  2016-08-12       Impact factor: 5.103

8.  Structure of the Ebola virus envelope protein MPER/TM domain and its interaction with the fusion loop explains their fusion activity.

Authors:  Jinwoo Lee; David A Nyenhuis; Elizabeth A Nelson; David S Cafiso; Judith M White; Lukas K Tamm
Journal:  Proc Natl Acad Sci U S A       Date:  2017-09-05       Impact factor: 11.205

Review 9.  Anti-Ebola therapies based on monoclonal antibodies: current state and challenges ahead.

Authors:  Everardo González-González; Mario Moisés Alvarez; Alan Roberto Márquez-Ipiña; Grissel Trujillo-de Santiago; Luis Mario Rodríguez-Martínez; Nasim Annabi; Ali Khademhosseini
Journal:  Crit Rev Biotechnol       Date:  2015-11-26       Impact factor: 8.429

10.  Ebola: Implications and Perspectives.

Authors:  Carlos Del Rio; Jeannette Guarner
Journal:  Trans Am Clin Climatol Assoc       Date:  2015
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