Literature DB >> 2249100

Mechanisms and clinical significance of resistance to new beta-lactam antibiotics.

D M Livermore1, M J Wood.   

Abstract

The newer beta-lactam antibiotics, including various ureidopenicillins, second- and third-generation cephalosporins, carbapenems and monobactams, are active against many bacteria that are resistant to older penicillins, such as ampicillin and ticarcillin. Nonetheless, resistance to the newer agents can arise, and in this article the mechanisms whereby it does so are reviewed and their clinical significance is discussed.

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Year:  1990        PMID： 2249100

Source DB:  PubMed          Journal:  Br J Hosp Med        ISSN： 0007-1064


  4 in total

Review 1.  Bacterial challenges and evolving antibacterial drug strategy.

Authors:  B Watt; J G Collee
Journal:  Postgrad Med J       Date:  1992-01       Impact factor: 2.401

Review 2.  The development of beta-lactam antibiotics in response to the evolution of beta-lactamases.

Authors:  S Y Essack
Journal:  Pharm Res       Date:  2001-10       Impact factor: 4.200

Review 3.  Penicillins. A current review of their clinical pharmacology and therapeutic use.

Authors:  Dilip Nathwani; Martin J Wood
Journal:  Drugs       Date:  1993-06       Impact factor: 9.546

4.  Comparison of the Sceptor Pseudomonas Plus MIC Panel with agar dilution for susceptibility testing of Pseudomonas aeruginosa.

Authors:  L F Joyce; K Stockman; J Downes; J H Andrew
Journal:  J Clin Microbiol       Date:  1992-10       Impact factor: 5.948
  4 in total

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