| Literature DB >> 2248733 |
L Steardo1, M Iovino, P Monteleone, M Bevilacqua, G Norbiato.
Abstract
Studies were carried out in the rat in order to investigate whether cholinergic mechanisms may be involved in vasopressin (VP) release induced by metoclopramide (MCP). The intravenous injection of MCP induced dose-related increases in plasma VP levels in water-loaded rats. These effects were prevented by atropine sulphate, but not by pirenzepine hydrochloride indicating that activation of cholinergic receptors of M-2 type was possibly required for the biologic response.Entities:
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Year: 1990 PMID: 2248733 DOI: 10.1007/bf01272764
Source DB: PubMed Journal: J Neural Transm Gen Sect