Literature DB >> 22486827

Trehalose glycolipids--synthesis and biological activities.

Ashna A Khan1, Bridget L Stocker, Mattie S M Timmer.   

Abstract

A variety of trehalose glycolipids have been isolated from natural sources, and several of these glycolipids exhibit important biological properties. These molecules also represent challenging synthetic targets due to their highly amphiphilic character, their large number of functional groups and additional chiral centres. This review highlights some of the recent advances made in the synthesis of trehalose glycolipids, and their associated biological activities.
Copyright © 2012 Elsevier Ltd. All rights reserved.

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Year:  2012        PMID： 22486827     DOI： 10.1016/j.carres.2012.03.010

Source DB:  PubMed          Journal:  Carbohydr Res        ISSN： 0008-6215            Impact factor:   2.104


  13 in total

1.  Tailoring Trehalose for Biomedical and Biotechnological Applications.

Authors:  Mara K O'Neill; Brent F Piligian; Claire D Olson; Peter J Woodruff; Benjamin M Swarts
Journal:  Pure Appl Chem       Date:  2017-01-11       Impact factor: 2.453

2.  The rv1184c locus encodes Chp2, an acyltransferase in Mycobacterium tuberculosis polyacyltrehalose lipid biosynthesis.

Authors:  Megan H Touchette; Cynthia M Holsclaw; Mary L Previti; Viven C Solomon; Julie A Leary; Carolyn R Bertozzi; Jessica C Seeliger
Journal:  J Bacteriol       Date:  2014-10-20       Impact factor: 3.490

3.  The effects of trehalose glycolipid presentation on cytokine production by GM-CSF macrophages.

Authors:  Bridget L Stocker; Kristel Kodar; Kanu Wahi; Amy J Foster; Jacquie L Harper; Daiki Mori; Sho Yamasaki; Mattie S M Timmer
Journal:  Glycoconj J       Date:  2019-01-08       Impact factor: 2.916

4.  6,6'-Aryl trehalose analogs as potential Mincle ligands.

Authors:  Omer K Rasheed; George Ettenger; Cassandra Buhl; Robert Child; Shannon M Miller; Jay T Evans; Kendal T Ryter
Journal:  Bioorg Med Chem       Date:  2020-05-31       Impact factor: 3.641

5.  Structural determination and Toll-like receptor 2-dependent proinflammatory activity of dimycolyl-diarabino-glycerol from Mycobacterium marinum.

Authors:  Elisabeth Elass-Rochard; Yoann Rombouts; Bernadette Coddeville; Emmanuel Maes; Renaud Blervaque; David Hot; Laurent Kremer; Yann Guérardel
Journal:  J Biol Chem       Date:  2012-07-13       Impact factor: 5.157

6.  Design of Trehalose-Based Amide/Sulfonamide C-type Lectin Receptor Signaling Compounds.

Authors:  Omer K Rasheed; Cassandra Buhl; Jay T Evans; Kendal T Ryter
Journal:  ChemMedChem       Date:  2021-02-09       Impact factor: 3.466

Review 7.  Surfactants tailored by the class Actinobacteria.

Authors:  Johannes H Kügler; Marilize Le Roes-Hill; Christoph Syldatk; Rudolf Hausmann
Journal:  Front Microbiol       Date:  2015-03-19       Impact factor: 5.640

8.  The Mincle ligand trehalose dibehenate differentially modulates M1-like and M2-like macrophage phenotype and function via Syk signaling.

Authors:  Kristel Kodar; Jacquie L Harper; Melanie J McConnell; Mattie S M Timmer; Bridget L Stocker
Journal:  Immun Inflamm Dis       Date:  2017-07-19

Review 9.  Identification and Biological Activity of Synthetic Macrophage Inducible C-Type Lectin Ligands.

Authors:  Chriselle D Braganza; Thomas Teunissen; Mattie S M Timmer; Bridget L Stocker
Journal:  Front Immunol       Date:  2018-01-17       Impact factor: 7.561

Review 10.  Mechanism of neuroprotection by trehalose: controversy surrounding autophagy induction.

Authors:  He-Jin Lee; Ye-Seul Yoon; Seung-Jae Lee
Journal:  Cell Death Dis       Date:  2018-06-15       Impact factor: 8.469
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