Literature DB >> 22484952

Sinensetin attenuates LPS-induced inflammation by regulating the protein level of IκB-α.

Hye-Sun Shin1, Seong-Il Kang, Seon-A Yoon, Hee-Chul Ko, Se-Jae Kim.   

Abstract

Sinensetin is one of the polymethoxyflavones (PMFs) having five methoxy groups on the basic benzo-γ-pyrone skeleton with a carbonyl group at the C(4) position. We investigated in this study the anti-inflammatory activity of sinensetin in lipopolysaccharide (LPS)-stimulated RAW 264.7 cells. Sinensetin showed anti-inflammatory activity by regulating the protein level of inhibitor κB-α (IκB-α).

Entities:  

Mesh：

Substances：

Year:  2012        PMID： 22484952     DOI： 10.1271/bbb.110908

Source DB:  PubMed          Journal:  Biosci Biotechnol Biochem        ISSN： 0916-8451            Impact factor:   2.043


  11 in total

1.  Hydrogen sulfide from a NaHS source attenuates dextran sulfate sodium (DSS)-induced inflammation via inhibiting nuclear factor-κB.

Authors:  Xi Chen; Xi-shuang Liu
Journal:  J Zhejiang Univ Sci B       Date:  2016-03       Impact factor: 3.066

2.  Anti-Inflammatory and Analgesic Effects of the Marine-Derived Compound Excavatolide B Isolated from the Culture-Type Formosan Gorgonian Briareum excavatum.

Authors:  Yen-You Lin; Sung-Chun Lin; Chien-Wei Feng; Pei-Chin Chen; Yin-Di Su; Chi-Min Li; San-Nan Yang; Yen-Hsuan Jean; Ping-Jyun Sung; Chang-Yih Duh; Zhi-Hong Wen
Journal:  Mar Drugs       Date:  2015-04-27       Impact factor: 5.118

3.  A Systematic Review of the Protective Actions of Cat's Whiskers (Misai Kucing) on the Central Nervous System.

Authors:  Yin-Sir Chung; Brandon Kar Meng Choo; Pervaiz Khalid Ahmed; Iekhsan Othman; Mohd Farooq Shaikh
Journal:  Front Pharmacol       Date:  2020-05-13       Impact factor: 5.810

4.  Sinensetin Induces Autophagic Cell Death through p53-Related AMPK/mTOR Signaling in Hepatocellular Carcinoma HepG2 Cells.

Authors:  Seong Min Kim; Sang Eun Ha; Ho Jeong Lee; Shailima Rampogu; Preethi Vetrivel; Hun Hwan Kim; Venu Venkatarame Gowda Saralamma; Keun Woo Lee; Gon Sup Kim
Journal:  Nutrients       Date:  2020-08-15       Impact factor: 5.717

5.  Kampo formulas alleviate aging-related emotional disturbances and neuroinflammation in male senescence-accelerated mouse prone 8 mice.

Authors:  Naoki Ito; Akiko Maruko; Kenshiro Oshima; Masaaki Yoshida; Kengo Honma; Chika Sugiyama; Takayuki Nagai; Yoshinori Kobayashi; Hiroshi Odaguchi; Norihiro Okada
Journal:  Aging (Albany NY)       Date:  2022-01-03       Impact factor: 5.682

6.  Sinensetin Attenuates Amyloid Beta25-35-Induced Oxidative Stress, Inflammation, and Apoptosis in SH-SY5Y Cells Through the TLR4/NF-κB Signaling Pathway.

Authors:  Zhongwen Zhi; Xiaohong Tang; Yuqian Wang; Rui Chen; Hu Ji
Journal:  Neurochem Res       Date:  2021-07-26       Impact factor: 3.996

7.  A soft coral-derived compound, 11-epi-sinulariolide acetate suppresses inflammatory response and bone destruction in adjuvant-induced arthritis.

Authors:  Yen-You Lin; Yen-Hsuan Jean; Hsin-Pai Lee; Wu-Fu Chen; Yu-Min Sun; Jui-Hsin Su; Yi Lu; Shi-Ying Huang; Han-Chun Hung; Ping-Jyun Sung; Jyh-Horng Sheu; Zhi-Hong Wen
Journal:  PLoS One       Date:  2013-05-13       Impact factor: 3.240

8.  Antioxidant and toxicity studies of 50% methanolic extract of Orthosiphon stamineus Benth.

Authors:  Mun Fei Yam; Chung Pin Lim; Lee Fung Ang; Lip Yee Por; Siew Tung Wong; Mohd Zaini Asmawi; Rusliza Basir; Mariam Ahmad
Journal:  Biomed Res Int       Date:  2013-12-30       Impact factor: 3.411

9.  Identification and Comparison of Constituents of Aurantii Fructus and Aurantii Fructus Immaturus by UFLC-DAD-Triple TOF-MS/MS.

Authors:  Yang Bai; Yuying Zheng; Wenjing Pang; Wei Peng; Hao Wu; Hongliang Yao; Panlin Li; Wen Deng; Jinle Cheng; Weiwei Su
Journal:  Molecules       Date:  2018-03-30       Impact factor: 4.411

10.  Sinensetin regulates age-related sarcopenia in cultured primary thigh and calf muscle cells.

Authors:  Jin-A Kim; Seong Min Kim; Sang Eun Ha; Preethi Vetrivel; Venu Venkatarame Gowda Saralamma; Eun Hee Kim; Gon Sup Kim
Journal:  BMC Complement Altern Med       Date:  2019-10-28       Impact factor: 3.659
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.