OBJECTIVE: The aim of this study was to assess the long-term risks of chronic kidney disease and arterial hypertension in living kidney donors. METHODS: Donors who were followed for more than 1 year after nephrectomy were included. We assessed each donor's blood pressure, urine protein, and estimated glomerular filtration rate (eGFR). RESULTS: The follow-up rate was 11% (154 out of 1,356 donors), only 19% of whom were followed by nephrologists. Blood pressure had increased from 113/75 to 116/77 mm Hg (P < .01), urinary protein excretion after donation did not increase, and renal function was well preserved after donor nephrectomy. However, 33 patients (21.4%) showed a decreased eGFR of <60 mL/min/1.73 m(2), and 3 donors developed end-stage renal disease that required renal replacement therapy. CONCLUSIONS: The follow-up rate of living donors after donation was low, and we observed an increased risk of developing chronic kidney disease after donation.
OBJECTIVE: The aim of this study was to assess the long-term risks of chronic kidney disease and arterial hypertension in living kidney donors. METHODS: Donors who were followed for more than 1 year after nephrectomy were included. We assessed each donor's blood pressure, urine protein, and estimated glomerular filtration rate (eGFR). RESULTS: The follow-up rate was 11% (154 out of 1,356 donors), only 19% of whom were followed by nephrologists. Blood pressure had increased from 113/75 to 116/77 mm Hg (P < .01), urinary protein excretion after donation did not increase, and renal function was well preserved after donor nephrectomy. However, 33 patients (21.4%) showed a decreased eGFR of <60 mL/min/1.73 m(2), and 3 donors developed end-stage renal disease that required renal replacement therapy. CONCLUSIONS: The follow-up rate of living donors after donation was low, and we observed an increased risk of developing chronic kidney disease after donation.
Authors: Allan B Massie; Abimereki D Muzaale; Xun Luo; Eric K H Chow; Jayme E Locke; Anh Q Nguyen; Macey L Henderson; Jon J Snyder; Dorry L Segev Journal: J Am Soc Nephrol Date: 2017-04-27 Impact factor: 10.121
Authors: Ngan N Lam; Krista L Lentine; Scott Klarenbach; Manish M Sood; Paul J Kuwornu; Kyla L Naylor; Gregory A Knoll; S Joseph Kim; Ann Young; Amit X Garg Journal: Can J Kidney Health Dis Date: 2018-04-09
Authors: Anna M Price; Nicola C Edwards; Manvir K Hayer; William E Moody; Richard P Steeds; Charles J Ferro; Jonathan N Townend Journal: J Am Soc Hypertens Date: 2018-05-09
Authors: Anjay Rastogi; Stanley Yuan; Farid Arman; Lewis Simon; Kelly Shaffer; Mohammad Kamgar; Niloofar Nobakht; Jonathan S Bromberg; Matthew R Weir Journal: Transplant Direct Date: 2019-09-19
Authors: Anna M Price; George H B Greenhall; William E Moody; Richard P Steeds; Patrick B Mark; Nicola C Edwards; Manvir K Hayer; Luke C Pickup; Ashwin Radhakrishnan; Jonathan P Law; Debasish Banerjee; Tunde Campbell; Charles R V Tomson; John R Cockcroft; Badri Shrestha; Ian B Wilkinson; Laurie A Tomlinson; Charles J Ferro; Jonathan N Townend Journal: Clin J Am Soc Nephrol Date: 2020-08-25 Impact factor: 8.237