Literature DB >> 22482903

Isolation and structural elucidation of abietic acid as the main adulterant in an herbal drug for the treatment of psoriasis.

Yi He1, Yumei Zhang, Jing Lu, Ruichao Lin.   

Abstract

An herbal drug for the treatment of psoriasis showed severe clinical adverse reactions. The main component of adulterant was isolated from the drug and its chemical structure was elucidated as abietic acid using NMR, HR-MS, and HPLC-DAD-MS. Although abietic acid had ever been used in clinical study for the treatment of psoriasis, it is not an approved drug. Its adulteration is very dangerous for the patients.
Copyright © 2012 Elsevier B.V. All rights reserved.

Entities:  

Mesh：

Substances：

Year:  2012        PMID： 22482903     DOI： 10.1016/j.jpba.2012.03.007

Source DB:  PubMed          Journal:  J Pharm Biomed Anal        ISSN： 0731-7085            Impact factor:   3.935


  2 in total

1.  A non-cytotoxic N-dehydroabietylamine derivative with potent antimalarial activity.

Authors:  Maralinganadoddi P Sadashiva; Raghavendra Gowda; Xianzhu Wu; Gajanan S Inamdar; Omer F Kuzu; Kanchugarakoppal S Rangappa; Gavin P Robertson; D Channe Gowda
Journal:  Exp Parasitol       Date:  2015-05-14       Impact factor: 2.011

2.  Preparation of functionalized porous nano-γ-Al2O3 powders employing colophony extract.

Authors:  Ángela B Sifontes; Brenda Gutierrez; Andrea Mónaco; Andreina Yanez; Yraida Díaz; Franklin J Méndez; Ligia Llovera; Edgar Cañizales; Joaquín L Brito
Journal:  Biotechnol Rep (Amst)       Date:  2014-07-21
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.