| Literature DB >> 22482498 |
Malin Parmar1, Anders Björklund.
Abstract
In this issue of Cell Stem Cell, Ma et al. (2012) report a differentiation protocol for generating striatal projection neurons from human embryonic stem cells with high efficiency. The cells survive transplantation, reconnect striatal circuitry, and restore motor function in a mouse model of striatal neurodegeneration that mimics the central pathohology of Huntington's disease.Entities:
Year: 2012 PMID: 22482498 DOI: 10.1016/j.stem.2012.03.004
Source DB: PubMed Journal: Cell Stem Cell ISSN: 1875-9777 Impact factor: 24.633